Serum 25-hydroxy-vitamin D (25-OHD) concentrations were measured in 49 patients with hepatobiliary disease in infancy. Low mean values were found in groups of patients with biliary atresia, neonatal hepatitis, choledochal cyst, and chronic intrahepatic cholestatic syndrome. In the group of patients with surgically repaired biliary atresia, the mean value did not differ from normal. Parenteral v...

Hepatitis E virus (HEV) infections lead to tens of thousands of deaths annually, mostly in developing countries. Hepatitis E poses a significant threat to the health of expectant mothers, a well-noted epidemiologic feature of the disease, but the contribution of vertically transmitted HEV infection to fetal and neonatal morbidity and mortality has received limited attention. Evidence assembled ...

A 12-year-old male child reported with history of fever for last seven years. Hepatosplenomegaly, hepatic and bone marrow granulomas were the main features. Idiopathic Granulomatous Hepatitis (IGH), a rare syndrome amenable to immunosuppressive therapy was diagnosed.

Hepatitis B infection during pregnancy can have serious consequences for both the mother and her infant. This study aimed to determine prevalence of hepatitis among pregnant women its effect on neonatal outcomes in a tertiary care hospital Pakistan. 120 were enrolled study, their demographic clinical data collected. The was 4.2% population. Infants born B-positive mothers more likely be prematu...

AIM Hepatobiliary scintigraphy is an integral part in the diagnostic work-up of the neonatal cholestasis syndrome. However, less than optimal specificity is its major disadvantage. Differentiation between biliary atresia and neonatal hepatitis is nearly impossible in some cases with poor hepatocellular function. 99mTc sestamibi (MIBI) is a cationic lipophilic agent which is a substrate of P-gly...

The Ponseti method is the standard of care for managing idiopathic congenital talipes equinovarus (clubfoot) in outpatient setting, but there are no clinical guidelines inpatient treatment. Children neonatal intensive unit (NICU) with clubfoot often delay treatment initiation due to medical reasons. We systematically reviewed literature related NICU, non-idiopathic clubfoot, and older infants, ...