The mannose-6-phosphate/insulin-like growth factor II receptor (M6P/IGF-IIR) is a multi-functional transmembrane glycoprotein whose major function is to bind and transport M6P-bearing glycoproteins from the trans-Golgi network or the cell surface to lysosomes. The cell surface M6P/IGF-IIR also bind and internalizes the insulin-like growth factor II. The receptor gene is considered a "candidate"...

BACKGROUND The reactive oxygen and nitrogen species generated during reperfusion of tissue are characteristic of intestinal ischemia and reperfusion (IIR) injury. OBJECTIVE This study was designed to assess whether the administration of aminoguanidine (AG), a selective nitric oxide synthase inhibitor, and/or melatonin has protective potential in IIR injury. METHODS Male Wistar albino rats (...

The hardware description and implementation of adaptive infinite-impulse-response (IIR) filters for real-time applications is an important and challenging designing issue. The aim of this paper is hardware description of digital adaptive IIR filters for implementing on field programmable gate array (FPGA) chips. The direct architecture is considered for IIR filter designing and Equation-Error (...

HRTFs (head-related transfer functions) are available for sound field reproduction with spatial fidelity, since HRTFs involve the acoustic cues such as interaural time difference, interaural intensity difference and spectral cues that are used for the perception of the location of a sound image. Generally, FIR filters are used in the simulation of HRTFs. However, this method is not useful for a...

Members of the transforming growth factor-beta (TGF-beta) superfamily signal through their cognate receptors to determine cell phenotypes during embryogenesis. Our previous studies on the regulation of first branchial arch morphogenesis have identified critical components of a hierarchy of different TGF-beta isoforms and their possible functions in regulating tooth and cartilage formation durin...

OBJECTIVE To investigate the anti-inflammatory and antioxidant effect of curcumin on lung lesion induced by intestinal ischemia reperfusion injury (IIR). METHODS Rats were divided into four groups: sham, intestinal IIR (IIR), 1 mg/kg of curcumin treatment group (1 mg/kg), and 5 mg/kg of curcumin treatment group (5 mg/kg). Curcumin was given respectively (1 mg/kg and 5 mg/kg) following the abo...

This study aimed at detecting possible patterns in the relationship between Anisosmotic Extracellular Regulation (AER) and Isosmotic Intracellular Regulation (IIR) in crustaceans and teleost fish from different habitats and evolutionary histories in fresh water (FW), thus different osmoregulatory capabilities, and degrees of euryhalinity. Crustaceans used were the hololimnetic FW Aegla schmitti...

A solution methodology for the design of digital infinite impulse response (IIR) filter considering multiple conflicting objectives has been proposed. The nucleus of the method is that multiple objectives can be attuned suitably, to optimize the performance in pass bands, stop bands and transition bands of IIR digital filters. The proposed method uses multiobjective optimization approach for de...

The parallel processing systolic array architecture is designed for the real time VLSI spatio temporal 3D Infinite Impulse Response (IIR) frequency planar filter to achieve high throughput of one frame per clock cycle (OFPCC). To reduce the circuit complexity by designing the architecture, that is based on differential form transfer function of a 3D IIR frequency planar filter. The 3D Look Ahea...

Design problem of infinite impulse response (IIR) filters is generally a non-linear optimization problem due to the presence of denominator polynomial. Additionally, the stability condition (position of poles) must be considered when optimizing the filter coefficients. Hence, an iterative optimization is usually required to solve the design problem for stable IIR filter. In this paper, we prese...