نتایج جستجو برای: il7r

تعداد نتایج: 206  

2016
Dao-Ping Sun Li Wang Chong-Yang Ding Jin-Hua Liang Hua-Yuan Zhu Yu-Jie Wu Lei Fan Jian-Yong Li Wei Xu

The factors involved in thymus regeneration after chemotherapy has not been sufficiently explored. This study was aimed to identify the clinical characteristics and single-nucleotide polymorphisms in the gene (IL7R) encoding IL-7Rα associated with thymus renewal after chemotherapy in Chinese Han individuals with lymphoma. The dynamics of thymic activity in 134 adults with Hodgkin lymphoma (HL) ...

Journal: :Journal of immunology 2005
Christine A Goetz Ian R Harmon Jennifer J O'Neil Matthew A Burchill Tanner M Johanns Michael A Farrar

The molecular mechanisms regulating lymphocyte lineage commitment remain poorly characterized. To explore the role of the IL7R in this process, we generated transgenic mice that express a constitutively active form of STAT5 (STAT5b-CA), a key downstream IL7R effector, throughout lymphocyte development. STAT5b-CA mice exhibit a 40-fold increase in pro-B cells in the thymus. As documented by BrdU...

2014
Yang Chen Xianxiang Xin Haiying Zhang Jianfeng Xu Yong Gao Aihua Tan Xiaobo Yang Xue Qin Yanling Hu Zengnan Mo

Erectile dysfunction (ED) is a global disease affecting a large number of people. Some studies have found a relationship between low-grade inflammation and ED. We hypothesized that the immune system might play a key role in the outcome of ED. Five immune agents (C3, C4, IgA, IgM, and IgG) were collected based on the Fangchenggang Area Male Health and Examination Survey (FAMHES), using methods o...

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