background: primary antibody deficiency, the most common primary immunodeficiency disorder, represents a heterogeneous spectrum of conditions caused by a defect in any critical stage of b cell development and is characterized by impaired production of normal amounts of antigen-specific antibodies. objective: this retrospective study aimed at description and analysis of demographic, clinical, im...

common variable immunodeficiency (cv id) is a heterogeneous primary immunodeficiency disorder, characterized by hypogammaglobulinemia and increased susceptibility to recurrent bacterial infections. to determine the spectrum of infectious complications in patients with common variable immunodeficiency (cv id), we reviewed the hospital records of 64 cvid patients, who were diagnosed in children&a...

background: although the efficacy of bacillus calmette-guerin (bcg) vaccine in the prevention of tuberculosis has been noted consistently, the use of bcg vaccine is not without risk. in this study we aimed to evaluate immunologically, children with complication of bcg vaccination in north of iran.materials and methods: this case-control study began in 30 jan 2013 and was completed in 2 jul 2015...

background: predicting life expectancy is an important component of public health, in that, it may affect policy making in fields such as social security and medical care., to estimate the life expectancy and the average years of life lost (ayll) of the human immunodeficiency virus (hiv)/acquired immunodeficiency syndrome (aids)-infected population, compared with that of the general population,...

conclusions hiv/hcv co-infection is an important medical problem in north-eastern poland. a history of incarceration and younger age at hiv diagnosis were additional to idu risk factors for hcv seropositivity in this cohort. patients and methods adult hiv-1 infected patients, with at least one antihcv result, treated in one of polish hiv/aids reference centers, participated in this cross-sectio...

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objective: primary immunodeficiency diseases (pid) are rare and heterogeneous congenital diseases leading to increased unusual susceptibility to developing infections and causingsome malignancies and autoimmune diseases. this study was conducted to evaluate the epidemiological characteristics of primary these diseases in patients attending the clinic of immunodeficiency diseases in kerman.subje...

major histocompatibility complex (mhc) class ii deficiency is a primary immunodeficiency disease characterized by abnormality of mhc class ii molecules surface expression on peripheral blood lymphocytes and monocytes. clinical manifestations include extreme susceptibility to viral, bacterial, and fungal infections but the immunodeficiency is not as severe as scid (severe combined immunodeficien...

The human immunodeficiency virus (HIV) is lentivirus (subgroup of retrovirus) which causes HIV infection and it acquired immunodeficiency syndrome (AIDS). HIV infection leads to low levels of CD4+T cells through number of mechanisms [1]. Our purpose is to review educative HIV prevention and control as Millennium Development Goal (MDG) and WHO's operational goal. In 2000, when ...