Introduction: Deficiencies of native antigliadin antibodies tests lead to the decrease of interest but, at the same time, to more serious studies of molecular biology in connection with this test. The discovery of specific B lymphocytes epitopes on certain deamidated gliadin molecules has led to a new serological test, the deamidated antigliadin antibodies. We aimed to evaluate these antibodies...

conclusions based on the findings of the present study, the frequency of toxoplasma infection is high in the studied population, although it is fairly close to the findings of reports from the other areas of iran. results in total, 1910 (29.87%) out of 6393 subjects were found to be infected with toxoplasma gondii. in terms of the seropositivity, 1871 (32.42%) out of 5770 and 128 (2.14%) out of...

Diffuse cutaneous leishmaniasis (DCL) is characterized by the presence of numerous nonulcerated nodules and plaques containing large numbers of Leishmania amazonensis parasites and few lymphoid elements. The immune responses of DCL patients reflect severe antigen-specific T-cell deficiencies, while the antibody response to Leishmania antigens is often accentuated. We report herein on the Leishm...

CBA/N mice express an X-linked deficiency in their antibody response to many bacterial carbohydrates; we have shown recently that these antigens normally elicit antibody responses predominantly of the IgM and IgG3 isotypes. Here we demonstrate that mice, with the CBA/N phenotype have perferential deficiencies of IgM and IgG3 immunoglobulin expression, both when measured in serum and in cells se...

The molecular bases of diseases of the epidermal appendages are gradually being elucidated as genes encoding their constituents and regulation are defined. A direct correspondence between altered protein sequence and aberrant hair shaft structure is evident in cases such as monilethrix (Schweizer, 2006). In others, gene defects lead to altered development and thus perturbed regulation of compon...

Immunoglobulin G subclass deficiency (IgGSCD) is a relatively common primary immunodeficiency disease (PI) in adults. The biological significance of IgGSCD in patients with chronic airway diseases is controversial. We conducted a retrospective study to characterize the clinical features of IgGSCD in this population. This study examined the medical charts from 59 adult patients with IgGSCD who h...

of skin products (protective creams, soaps, body lotions, shampoos, etc.). It has been suggested that sensitization to proteins from certain foods such as coconuts could be due to topical exposure through the skin. Whether it is through this route or the oral route by ingestion of foods containing products derived from coconuts, it is very probable that exposure to coconut proteins is now occur...