نتایج جستجو برای: immunomodulation therapy
تعداد نتایج: 656734 فیلتر نتایج به سال:
Abstract Diabetic foot ulcer (DFU) is one of the most common complications diabetes, bringing physical and mental challenges for patients due to lack efficient curative therapy. Despite considerable advances in pharmacological surgical approaches, clinical trials DFU remain disappointing local overactive excessive inflammation. Immunomodulatory hydrogels has significant advantages overcome chal...
Type 1 diabetes (T1D) and latent autoimmune in adults (LADA) represent the most common types of are characterized by different age onset, degrees immune-mediated destruction pancreatic beta cells rates disease progression towards insulin dependence. Several immunotherapies aimed to counteract responses against preserve beta-cell function currently being investigated, particularly T1D. Prelimina...
BACKGROUND Histone deacetylase (HDAC) inhibitors are a class of agents that have potent antitumor activity with a reported ability to upregulate MHC and costimulatory molecule expression. We hypothesized that epigenetic pharmacological immunomodulation could sensitize tumors to immune mediated cell death with an adoptive T cell therapy. METHODS The pan-HDAC inhibitor, LBH589, was combined wit...
Multipotent adult progenitor cells (MAPCs) are an adherent stem cell population that belongs to the mesenchymal-type progenitor cell family. Although MAPCs are emerging as candidate agents for immunomodulation after solid organ transplantation, their value requires further validation in a clinically relevant cell therapy model using an organ donor- and organ recipient-independent, third-party c...
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