To take advantage of conservation tillage systems (including direct drilling and non-inversion) in central Iran, it is important to study the effects of different cultivation practices on soil structural stability as a physical indicator. A four-year study was conducted to investigate the effects of seven tillage systems on aggregate properties of a clay-loam soil (Calcic Cambisol) with continu...

Several developments and investigations have been done to automate the lateral control of hoes with the aim to achieve higher weeding efficiency and decreased labor costs. The aim of this project was to investigate the accuracy and limitations for a computer controlled hoeing operation based on a GPS system. A conventional hoe and an electro-hydraulic side shift frame was used and attached to a...

The involvement of bradykinin in virus-induced airway hyperresponsiveness (AHR) in guinea pig airways in vivo was determined with the B(2)-receptor antagonist Hoe 140. The efficacy of Hoe 140 treatment was assessed through its effect on the bradykinin-induced (up to 2.5 microgram/100 g B.W. administered intravenously) decrease in blood pressure (BP). Hoe 140 (0.1 micromol/kg), administered subc...

The mechanism of the enhanced vascular permeability and retention (EPR) effect seen in solid tumors was investigated with sarcoma 180 (S-180) in mice by using the bradykinin receptor antagonist D-Arg-[Hyp3,Thi5,D-Tic7,Oic8]bradykinin] (HOE 140), the nitric oxide (NO) scavenger 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (PTIO), and the cyclooxygenase (prostaglandin synthase) inhibito...

Materials and Methods Varieties selected for the 2003 organic soybean variety trial included the following: IA3011, IA3021, IA3022, Pioneer 9305, Schillinger 240F.Y, and Schillinger 290F.HP. Plots measuring 20 × 40 feet were laid out in a completely randomized block design with four replications of each variety. Soybeans were planted at a depth of 2 inches on May 28, 2003, at a rate of 200,000 ...

The contribution of endogenous kinins to the chronic antihypertensive effect of angiotensin converting enzyme inhibitors was investigated in two-kidney, one clip hypertensive Wistar rats, using the new bradykinin B2-receptor antagonist HOE 140 (D-Arg, [Hyp3, Thi5, D-Tic7, Oic8]-bradykinin). In a first protocol, rats were pretreated orally with the angiotensin converting enzyme inhibitor ramipri...

In humans, bradykinin contributes to the acute renin response after ACE inhibition. To further explore the role of endogenous bradykinin in human renin regulation, we determined the effect of HOE 140, a specific bradykinin B(2) receptor antagonist, on the renin response to 0.5 mg/kg i.v. furosemide in a randomized, single blind, crossover design study of 10 healthy, salt-replete volunteers. HOE...