Sliding clamps are loaded onto DNA by clamp loaders to serve the critical role of coordinating various enzymes on DNA. Clamp loaders must quickly and efficiently load clamps at primer/template (p/t) junctions containing a duplex region with a free 3'OH (3'DNA), but it is unclear how clamp loaders target these sites. To measure the Escherichia coli and Saccharomyces cerevisiae clamp loader speci...

Mathematical chemistry is a branch of theoretical chemistry for discussion and prediction of the molecular structure using mathematical methods without necessarily referring to quantum mechanics. In theoretical chemistry, distance-based molecular structure descriptors are used for modeling physical, pharmacologic, biological and other properties of chemical compounds. The Wiener Polarity index ...

Three types of solvents with different polarity (cyclohexane, toluene and benzene), a nonionic surfactant Span 40 were used to prepare strontium aluminate (SrAl2O4) spinel nanoparticles by a reverse micelle method. The structure of SrAl2O4 nanoparticles was characterized by X-ray diffraction (XRD). The morphology and size of the synthesized materials were studied using field emission scanning e...

background: antibiotics can be life saving if they are used correctly, and can have unwanted side effects specially resistance with incorrect use. unfortunately in fear of no response, physicians use broad spectrum antibiotics meticulously. in this drug utilization evaluation (due), improper use of vancomycin and five broad-spectrum antibiotics are studied to find faults and solution for this p...

For elastic reverse-time migration, one constructs elastic source and receiver wavefields using a source function and multi-component data, and then applies an imaging condition to the reconstructed wavefields. A widely used imaging condition is crosscorrelation of individual wave modes separated in both wavefields, e.g., compressional (P) waves and shear (S) waves. One difficulty in elastic mi...

Twitter is a platform which may contain opinions, thoughts, facts and other information. Within it, many and various communities are originated by users with common interests, or with similar ways to feel part of the community. This paper presents a possible combined approach between Social Network Analysis and Sentiment Analysis. In particular, we have tried to associate a sentiment to the nod...

We have investigated the role of the homeodomain transcription factor genes En-1 and En-2, homologs of the Drosophila segment polarity gene engrailed, in regulating the development of the retinotopic map in the chick optic tectum. The En proteins are distributed in a gradient along the rostral-caudal axis of the developing tectum, with highest amounts found caudally. Previous evidence suggests ...