AIM To validate high definition endoscopes with Fujinon intelligent chromoendoscopy (FICE) in colonoscopy. METHODS The image quality of normal white light endoscopy (WLE), that of the 10 available FICE filters and that of a gold standard (0.2% indigo carmine dye) were compared. RESULTS FICE-filter 4 [red, green, and blue (RGB) wavelengths of 520, 500, and 405 nm, respectively] provided the ...

AIMS The purpose of this study was to compare the diagnostic performance of an immunoassay for placental alpha microglobulin-1 (PAMG-1) in vaginal fluid with the intra-amniotic instillation of indigo carmine for the diagnosis of membrane rupture in patients with an equivocal status. METHODS A prospective multi-site study was performed involving women reporting signs, symptoms, or complaints s...

Two sensitive spectrophotometric methods are presented for the assay of pantoprazole sodium sesqui hydrate (PNT) in bulk drug and in formulations using Nbromosuccinimide (NBS) and two dyes, methyl orange and indigo carmine, as reagents. The methods involve the addition of a known excess of NBS to PNT in acid medium, followed by determination of unreacted oxidant by reacting with a fixed amount ...

One titrimetric and two indirect spectrophotometric methods are described for the determination of doxycycline hyclate (DCH) in bulk drug and in its formulations. The methods use bromate-bromide, methyl orange and indigo carmine as reagents. In titrimetry (method A), DCH is treated with a known excess of bromate-bromide mixture in acid medium and the residual bromine is back titrated iodometric...

We have found that photo-excited indigo carmine causes stepwise proton transfer to generate monoalcohol intermediate, which immediately returns to the parent molecule [I. Iwakura, A. Yabushita, T. Kobayashi, Chem. Lett. 38 (2009) 1020]. The kinetic isotope effect in the proton transfer of this system has been studied by direct observation of the real-time molecular vibrational amplitude during ...