Rats and mice were vasectomized to study the pathological changes in the development and resolution of vasectomy induced sperm granuloma. Epididymal weights were increased in all groups of vasectomized animals, whereas testicular weights did not change. Granuloma in the form of yellow nodular masses of cysts were present at the lower pole of the epididymis. It consisted of a pool of sperm and o...

Foreign body granulomas from sutures are more common among non-absorbable compared to absorbable and have been reported as a postoperative complication in variety of medical fields. However, only few cases delayed foreign reaction addressed with orthopedics. We present patient systemic lupus erythematosus who developed an infectious suture granuloma that extended the entire Achilles tendon was ...

The effects of methanol extract of Phyllanthus amarus on different phases of in lammation were examined. Investigations were performed using different phlogistic agents-induced paw e ema, carrageenan-induced airpouch inflammation and cotton pellet granuloma in rats. Methanol extract of Phyllanthus amarus significantly inhibited carrageenan, bradykinin, serotonin and prostaglandin E1-induced paw...

in the present study, anti-anaphylactic, anti-inflammatory and membrane stabilizing properties of a lupine alkaloid plumerianine (compound 1), isolated from the root bark of plumeria acutifolia poir were investigated in animal models. the anti-anaphylactic activity of compound 1 (10, 25 and 50 mg/kg) was studied by using models such as passive cutaneous anaphylaxis, passive paw anaphylaxis and ...

The present study was designed to assess the cytotoxicity, anti-inflammatory and analgesic properties of methanol extract of Woodfordia fruticosa flowers. Cytotoxic activity of methanol extract of Woodfordia fruticosa flowers was tested using Artemia salina (Brine shrimp) bioassay. Two doses (400 and 600 mg/Kg) were evaluated for the anti-inflammatory activity against the carrageenan, histamine...

Joshanda, a polyherbal product is commonly used to treat inflammation of the mucous membranes of nose and air passages. The current study was planned to evaluate the antiinflammatory and antioxidant activity of Decoction of Joshanda (DJ). DJ was challenged in carrageenan induced paw edema and cotton pellets induced granuloma at 100, 200 and 300 mg/kg i.p. for its antiinflammtory profile. Howeve...

BACKGROUND In response to Mtb infection, the host remodels the infection foci into a dense mass of cells known as the granuloma. The key objective of the granuloma is to contain the spread of Mtb into uninfected regions of the lung. However, it appears that Mtb has evolved mechanisms to resist killing in the granuloma. Profiling granuloma transcriptome will identify key immune signaling pathway...

Shorea robusta Gaertn. f. (Sal) is one of the most important traditional Indian medicinal plants. The resin of the plant has been used in the treatment of inflammation in folklore medicine. In the present study, ethanolic extract (70%) of S. robusta resin (SRE) was investigated for its anti-inflammatory and antipyretic activities. Acute inflammation was produced by carrageenan-induced hind paw ...

Granuloma annulare induced by scabies infection has been described previously in three patients. In this report, we share our observation of a fourth case.

Aim: To investigate the analgesic and anti-inflammatory properties of seed extracts of Diplocyclos palmatus (L) C. Jeffrey. Methods: Three extracts of different polarity of Diplocyclos palmatus (L) C. Jeffrey seeds were tested for their analgesic and anti-inflammatory activities. Analgesic activity was evaluated using the hot plate and acetic acid-induced writhing in mice. Antiinflammatory acti...