Background: Osseous metaplasia occurring within the gastrointestinal tract is a rare phenomenon. Only a few of cases have been documented that osseous metaplasia can occur in colorectal polyps, although its underlying pathogenesis has not yet been elucidated. Methods: Two cases of osseous metaplasia within inflammatory and adenomatous polyps of colon, respectively. The clinical and histological...

Glucocorticoids (GCs) bind to the cellular glucocorticoid receptors (GRs) to exert anti-inflammatory and immunosuppressive actions. We investigated the changes in the expressions of the two GR isoforms, GR-alpha and GR-beta, in nasal polyps treated with GC. Immunofluorescent staining revealed prominent expression of GR-alpha in the inflammatory cell infiltrate in the polyps obtained from patien...

UNLABELLED Rhinosinusal polyps physiopathology is not fully understand, despite numerous hypotheses regarding its inflammatory process. AIMS A prospective study regarding the gene expression of proteins: anexin-1 and galectin-1, which has an anti-inflammatory action and is modulated by steroids. MATERIALS AND METHODS Eleven patients with rhinosinusal polyps suffered a biopsy of their polyps...

Inflammatory fibroid polyps are uncommon but well documented as solitary polyps occurring typically in the stomach or ileum. A Devon family has previously been reported in which a female in three successive generations has presented with multiple polyps requiring repeated surgery over a number of years. A further two female family members, both siblings from the 3rd generation, who required sur...

Screening Colonoscopy A screening colonoscopy is done to check for cancer and inflammatory diseases like ulcerative colitis. Most colorectal cancers (CRC) start as non-cancerous polyps (tiny, fast growing cells that may become cancer). Removing polyps or finding cancer at an early stage can increase your chances for a full recovery.2 During the colonoscopy, polyps can be removed with tiny instr...

Intussusceptions are defined as the telescoping of one segment of the gastrointestinal tract into an adjacent distal segment. In the small bowel, intussusceptions are typically caused by benign processes, but can occasionally be caused by inflammatory fibroid polyps, which often present as intussusception and bowel obstruction. These polyps are rare, benign, tumorous lesions in the gastrointest...

Inflammatory cell populations have not been yet precisely evaluated in cystic fibrosis (CF) airways. We intended to characterize morphological modifications, inflammatory cell infiltration and cell proliferation in nasal tissues obtained from 15 CF patients and from 6 non-CF patients with nasal polyposis. Morphological analysis showed an intense inflammatory infiltration in CF and non-CF tissue...

BACKGROUND Chronic rhinosinusitis is a multifactorial process disease in which bacterial infection or colonization may play an important role in the initiation or persistence of inflammatory response. The association between mucosal bacteria presence and inflammatory patterns has only been partially explored. OBJECTIVE To demonstrate specific mucosal microorganisms possible association with i...