نتایج جستجو برای: inhaler

تعداد نتایج: 3665  

Journal: :Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2000
M R Feddah K F Brown E M Gipps N M Davies

PURPOSE To study the influence of inspiratory flow rate on the fine particle mass and the particle size distribution for metered dose inhaler (MDI) and dry powder inhaler (DPI) glucocorticoid products, in vitro. To compare the performance of MDI and DPI inhalers containing the same drug and strength at an impaction flow rate of 60 L/min. METHODS The Marple Miller cascade impactor model 150 an...

2018
Omar Sharif Usmani Federico Lavorini Jonathan Marshall William Christopher Nigel Dunlop Louise Heron Emily Farrington Richard Dekhuijzen

BACKGROUND Inhaled drug delivery is the cornerstone treatment for asthma and chronic obstructive pulmonary disease (COPD). However, use of inhaler devices can be challenging, potentially leading to critical errors in handling that can significantly reduce drug delivery to the lungs and effectiveness of treatment. METHODS A systematic review was conducted to define 'critical' errors and their ...

2017
Alpesh N Amin Vaidyanathan Ganapathy Adam Roughley Mark Small

BACKGROUND Improper use of bronchodilators is associated with poor disease control, nonadherence to long-term therapy, and poor clinical outcomes. Our current understanding of factors associated with correct inhaler use and adherence is limited. We measured physician-and patient-reported confidence in device usage and associations with treatment adherence and COPD-related health status. METHO...

2016
Janine A. M. Westerik Victoria Carter Henry Chrystyn Anne Burden Samantha L. Thompson Dermot Ryan Kevin Gruffydd-Jones John Haughney Nicolas Roche Federico Lavorini Alberto Papi Antonio Infantino Miguel Roman-Rodriguez Sinthia Bosnic-Anticevich Karin Lisspers Björn Ställberg Svein Høegh Henrichsen Thys van der Molen Catherine Hutton David B. Price

OBJECTIVE Correct inhaler technique is central to effective delivery of asthma therapy. The study aim was to identify factors associated with serious inhaler technique errors and their prevalence among primary care patients with asthma using the Diskus dry powder inhaler (DPI). METHODS This was a historical, multinational, cross-sectional study (2011-2013) using the iHARP database, an interna...

Journal: :BMJ 1998
J G Ayres C D Frost W F Holmes D R Williams S M Ward

OBJECTIVE To evaluate the safety of a non-chlorofluorocarbon metered dose salbutamol inhaler. DESIGN This was a postmarketing surveillance study, conducted under formal guidelines for company sponsored safety assessment of marketed medicines (SAMM). A non-randomised, non-interventional, observational design compared patients prescribed metered doses of salbutamol delivered by inhalers using e...

2006
Paula Anderson

Events of the past decade have stimulated development of new drug formulations and delivery devices that have improved the efficiency, ease of use, and environmental impact of inhaled drug therapy. Respimat Soft Mist Inhaler is a novel, multidose, propellant-free, hand-held, liquid inhaler that represents a new category of inhaler devices. The aerosol cloud generated by Respimat contains a high...

Journal: :The Lancet 1910

2014
Elaine Mac Hale Richard W. Costello Seamus Cowman

AIM To examine the impact of a nurse-led patient assessment and education programme in promoting compliance with inhaler use in asthma patients. DESIGN A quasi-experimental pre-test and post-test design. METHODS A sample of asthmatic patients (N = 21) were recruited from the population of patients attending an asthma clinic. An Inhaler Proficiency Schedule (IPS) was developed and validated....

Journal: :Thorax 2012
Mitesh Patel Janine Pilcher

Received 17 September 2012 Accepted 21 September 2012 CHEST CLINIC Case based discussion JP: A 25-year-old gentleman with asthma attended for routine out-patient review. As part of this consultation, his current symptoms and recent inhaler use were discussed, including whether he ever left home without his reliever inhaler. Though his asthma was well controlled, he reported that he always carri...

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