The intervening zone (IZ) is a pool of progenitor cells located at the midbrain-hindbrain boundary (MHB) and important for MHB maintenance, midbrain-hindbrain growth and the generation of midbrain-hindbrain neurons. Recently, we implicated the Hairy/E(spl) transcription factor Her5 in the formation of the medial (most basal) part of the IZ (MIZ) in zebrafish; the molecular bases for lateral IZ ...

Semecarpus anacardium is a toxic nature plant and it belongs to family Anacardiaceae.It well known for its use in ayurveda siddha as potent medicinal herb since ancient times. According Ayurveda also named Bhallataka Dhobi nut. Phytochemical pharmacological analyses of nut extracts shows variety bioactive compounds such bioflavonoids, bhilawanols, phenolic compounds, minerals glycosides which v...

Background and Aim: This study aimed to compare the effects of acetone and ethanolic extracts of Plantago major (P. major) on S. mutans.   Materials and Methods: In this in vitro study, the antibacterial effects of eight different concentrations of the acetone and ethanolic extracts of P. major seed were examined on S. mutans, and the minimum inhibitory concentration (MIC) and minimum bacte...

Sericostoma pauciflorum Stocks ex Wight(Family Boraginaceae) used against cancer, diabetes and known to be health promoter. Callus cultures have been established from the stem explants on Murashige and Skoog (MS) medium supplemented with 1.5 mg/L concentration of different growth hormone viz. kinetin (Kn), indole 3-acetic acid (IAA) and indole 3-butyric acid (IBA). At 6 weeks of age, these call...

Many local governments are adopting inclusionary zoning (IZ) as a means of producing affordable housing without direct public subsidies. In this paper, panel data on IZ in the San Francisco metropolitan area and suburban Boston are used to analyse how much affordable housing the programmes produce and how IZ affects the prices and production of market-rate housing. The amount of affordable hous...

The radial migration of neuronal progenitor cells is critical for the development of cerebral cortex layers. They go through a critical step transforming from multipolar to bipolar before outward migration. A Disintegrin and Metalloprotease 17 (ADAM17) is a transmembrane protease which can process many substrates involved in cell-cell interaction, including Notch, ligands of EGFR, and some cell...

Most neurons migrate with an elongated, "bipolar" morphology, extending a long leading process that explores the environment. However, when immature projection neurons enter the intermediate zone (IZ) of the neocortex they become "multipolar". Multipolar cells extend and retract cytoplasmic processes in different directions and move erratically-sideways, up and down. Multipolar cells extend axo...

introduction: the antimicrobial efficacy of root canal irrigant plays an important role in increasing the success of root canal treatment (rct). the aim of the present experimental study was to compare the antimicrobial activity of triphala (a plant-derived solution) with 0.5, 1, 2.5 and 5% concentrations of sodium hypochlorite (naocl), against enterococcus faecalis ( e. faecalis ). methods and...

PURPOSE To characterize the optical coherence tomography (OCT) appearances of photoreceptor degeneration in the rhodopsin P23H transgenic rat (line 2) in relation to the histological, ultrastructural, and electroretinography (ERG) findings. MATERIALS AND METHODS Homozygous rhodopsin P23H transgenic albino rats (line 2, very-slow degeneration model) were employed. Using OCT (Micron IV®; Phoeni...

Recent studies indicate that GABA acts as a chemoattractant during rat cortical histogenesis. In vivo, GABA localizes in appropriate locations for a chemoattractant, along migratory routes and near target destinations for migrating cortical neurons. In vitro, GABA induces dissociated embryonic cortical neurons to migrate. Here, embryonic rat cortical slices were cultured in the presence or abse...