In this article we prove a collection of new non-linear and non-local integral inequalities. As an example for u ≥ 0 and p ∈ (0,∞) we obtain ∫ R3 dx u(x) ≤ ( p+ 1 p )2 ∫ R3 dx {(−4)−1u(x)}|∇u p 2 (x)|. We use these inequalities to deduce global existence of solutions to a non-local heat equation with a quadratic non-linearity for large radial monotonic positive initial conditions. Specifically,...