The Silky Fowl (SF) is known for its special phenotypes and atypical distribution of melanocytes among internal organs. Although the genes associated with melanocyte migration have been investigated substantially, there is little information on the postnatal distribution of melanocytes in inner organs and the effect of hyperpigmentation on the development of SF. Here, we analyzed melanocyte dis...

Abstract Introduction There is an association between frailty and arterial stiffness. However, stiffness does not uniformly correlate with the spectrum of states. Both oxidative stress inflammaging contribute to vascular aging. are no human studies exploring links stiffness, stress, frailty. Our objective investigate as predictors Methods An observational longitudinal cohort study will be used ...

objective: annexin a1 (anxa1) is suggested to have anti-inflammatory function. however, the precise function of anxa1 has remained unclear. in this study, we therefore examined the potency of anxa1 in regulating reactive oxygen species (ros) production and suppressing pro-inflammatory responses in pc12 cells induced by 1-methyl-4-phenylpyridinium (mpp+). materials and methods: in this experimen...

BACKGROUND Helicobacter pylori is the main risk factor for the development of non-cardia gastric cancer. Increased proliferation of the gastric mucosa is a feature of H. pylori infection. Mucosal interkeukin-1beta production is increased in H. pylori infection and IL-1beta genotypes associated with increased pro-inflammatory activity are risk factors for the development of gastric cancer. The e...