OBJECTIVES Haemodynamic parameters for predicting fluid responsiveness in intensive care patients are invasive, technically challenging or not universally applicable. We compared the initial systolic time interval (ISTI), a non-invasive measure of the time interval between the electrical and mechanical activities of the heart measured by impedance cardiography, with invasively measured haemodyn...

Introduction: Electrical impedance of tissues on low frequencies includes useful information about functional and structural changes in tissues. This property is used in Electrical Impedance Tomography (EIT) imaging modality for the detection of lesions in tissues.Objective: The goal of this article is to study changes in electrical impedance of tissues in the presence of gold nanoparticles.Mat...

Antenatal exposure to intra-amniotic (i.a.) endotoxin initiates a complex series of events, including an inflammatory cascade, increased surfactant production, and alterations to lung structure. Using the low frequency forced oscillation technique as a sensitive tool for measurement of respiratory impedance, we aimed to determine which factors contributed most to measured changes in lung mechan...

The harmonic impedance spectra (HIS) of a time-varying bioimpedance Z(ω, t) is a new tool to better understand and describe complex time-varying biological systems with a distinctive periodic character as, for example, cardiovascular and respiratory systems. In this paper, the relationship between the experimental setup and the identification framework for estimating Z(ω, t) is set up. The theo...

INTRODUCTION Patients after out-of-hospital cardiac arrest (OHCA) benefit from therapeutic hypothermia for 24 hours. The time needed to reach hypothermia (target temperature of 32 degrees C to 34 degrees C) varies widely. In this study, we explore the relation between measures of body composition and the time needed to reach target temperature with hypothermia. METHOD We conducted a prospecti...

The rate adaptive sensors applied to cardiac pacing should respond as promptly as the normal sinus node with an highly specific and sensitive detection of the need of increasing heart rate. Sensors operating alone may not provide optimal heart responsiveness: central venous pH sensing, variations in the oxygen content of mixed venous blood, QT interval, breathing rate and pulmonary minute venti...

BACKGROUND Ablation lesion depth caused by radiofrequency-based renal denervation (RDN) was limited to <4 mm in previous animal studies, suggesting that radiofrequency-RDN cannot ablate a substantial percentage of renal sympathetic nerves. We aimed to define the true lesion depth achieved with radiofrequency-RDN using a fine sectioning method and to investigate biophysical parameters that could...