PURPOSE The aim of this work was to study the International Commission on Radiation Unit and Measurement (ICRU) for rectum (rICRU) and bladder (bICRU) dose behaviors in the treatment of cervical cancer by high dose rate (HDR) intracavitary brachytherapy (ICRT). MATERIAL AND METHODS A retrospective study was carried out on 38 patients with a total of 38 fractions (1st fraction of each patient)...

OBJECTIVE To evaluate the interindividual and intraindividual applicator position variability in high dose rate ring and tandem intracavitary brachytherapy applications in locally advanced cervical cancer. PATIENTS AND METHODS Eight patients with locally advanced cervical cancer formed the study population. They had been treated in Dokuz Eylül University Department of Radiation Oncology betwe...

BACKGROUND A current paradigm in the treatment of cervical cancer with radiation therapy is that intracavitary brachytherapy is an essential component of radical treatment. This is a matched retrospective comparison of the results of treatment in patients treated with external beam chemoradiation (EBRT-CT) and radical hysterectomy versus those treated with identical chemoradiation followed by b...

Conventional radiotherapy for cervical cancer relies on clinical examination, 3-dimensional conformal radiotherapy (3D-CRT), and 2-dimensional intracavitary brachytherapy. Excellent local control and survival have been obtained for small early stage cervical cancer with definitive radiotherapy. For bulky and locally advanced disease, the addition of chemotherapy has improved the prognosis but t...

PURPOSE The purpose of this study was to demonstrate the dosimetric and clinical feasibility of image guided radiation therapy (IGRT) combined with high-dose-rate (HDR) intracavitary brachytherapy (ICBT) to improve dose distribution in cervical cancer treatment. MATERIAL AND METHODS For 42 cervical cancer patients, magnetic resonance imaging (MRI) scans were acquired after completion of whole...

PURPOSE Three-dimensional (3D) printing technology allows physicians to rapidly create customized devices for patients. We report our initial clinical experience using this technology to create custom applicators for vaginal brachytherapy. MATERIAL AND METHODS Three brachytherapy patients with unique clinical needs were identified as likely to benefit from a customized vaginal applicator. Pat...

Background: In intracavitary brachytherapy for gynecological cancers, various techniques are used to locate the anterior rectal wall nearest to the sources but there is no consensus on the best method to do so. This study aimed to compare a technique used routinely in some centers that employs a wire marker to locate the position of the maximum rectal dose point, versus the method recommended b...

By the early 1950s, after its discovery and implementation in medicine, brachytherapy (BT) had become a wellestablished modality of treatment.. As it is today, intracavitary brachytherapy (ICBT) was used to deliver most of the central tumor dose for cervical cancer [1]. Because of the developments in external beam radiotherapy, allowing delivery of doses to deep tumors competitive with those ac...