The origin of the intrahepatic bile ducts in the embryonic mouse liver was investigated. At 12.5 and 13.5 gestation days in the C3H/Tw strain mouse, the liver parenchyma contains morphologically and histochemically homogeneous immature hepatocytes but not bile duct cells. When the liver fragments were cultured in the testis, immature hepatocytes differentiated into large hepatocytes for the mos...

Hydatid disease (HD) is a unique parasitic disease that primarily affects the liver and is endemic in many parts of the world. There are four types of hydatid cysts (HCs) with various levels of organ involvement. All four HC types can be seen in the liver, with the right lobe being the most common site of involvement. There are many potential intrahepatic and extrahepatic complications that aff...

BACKGROUND We aimed to evaluate the feasibility and clinical significance of using a modified liver-mobilization technique to treat renal cell carcinoma (RCC) combined with intrahepatic inferior vena cava (IVC) thrombosis. METHODS A total of 11 level III thrombus patients underwent radical nephrectomy with resection of the tumor thrombus from intrahepatic IVC. A father clamp was used in combi...

UNLABELLED Intrahepatic heterotopic pancreas is rarely reported in the literature. Here, we report a case of a 39-year-old male with intrahepatic heterotopic pancreas associated with primary cholesterol hepatolithiasis. Computed tomography (CT) scans revealed multiple cholesterol stones in intrahepatic bile ducts of the left lobe concomitant with intrahepatic cholangiectases. These observations...

AIMS To determine how chronic hepatitis D virus (HDV) infection affects intrahepatic hepatitis B virus (HBV) antigen expression. METHODS Ninety eight liver biopsy specimens from 68 patients seropositive for total antibody to HDV were studied by immunohistochemistry, and the amount of HBV antigens was also quantified by radioimmunoassay in 12 patients and compared with 30 patients with chronic...

Biliary cast syndrome (BCS) is an unusual complication of orthotopic liver transplantation (OLT). BCS is characterized by multiple intrahepatic biliary strictures, ductal dilatation, intrahepatic abscesses, and biliary anastomotic leakage. The symptoms of BCS usually include high fever, jaundice and cholestatic liver enzyme elevation; similar to the symptoms observed in some patients with intra...

AIM To explore the effects of matrine (MT) on acute intrahepatic cholestasis induced by 17alpha-ethinyl estradiol (EE) in rats. METHODS Acute intrahepatic cholestasis in rats were induced by EE, and the effects of MT on acute intrahepatic cholestasis were explored and compared with ursodeoxycholic acid (UDCA) by serum biochemical determination and bile excretion experiments. RESULTS The ser...

A 65-year-old female presenting with hepatobiliary cystadenoma (HC) comprised of multiple cysts in the liver and a non-specific epigastric pain is reported herein.  Ultrasound study demonstrated dilated common bile duct (CBD) and intrahepatic bile ducts, plus two spherical stone-like bodies filling defects in the proximal CBD. Sphincterotomy and basket performed for the patient were not success...