OBJECTIVE Granulomatosis with polyangiitis (GPA) is a necrotizing inflammatory disease that can affect the airway. The purpose of this study was to present a case of pediatric laryngotracheal GPA and provide management recommendations based on a thorough review of the literature. DATA SOURCES Retrospective chart and literature review REVIEW METHODS: A pediatric patient with laryngotracheal an...

a 47 year-old woman presented with eight-month history of tattoo allergic reaction of eyebrows after botulinum toxin a injection that was resistant to oral, topical and intralesional injection of corticosteroids. multiple sessions of treatment with co2 fractional laser resulted in significant flattening of allergic papules and plaques as well as reduction of tattoo pigmentation

OBJECTIVE To demonstrate imaging findings during the follow-up of patients with aneurysmal bone cyst (ABC) of C2 treated with intralesional injection of calcitonin and methylprednisolone. METHOD Three patients with ABC of C2 were treated percutaneously with intralesional injection of calcitonin and methylprednisolone. All the patients were females, with ages varying from 6 to 13 years. All of...

OBJECTIVE To compare the efficacy of intralesional triamcinolone and topical betamethasone in the management of localized alopecia areata. STUDY DESIGN A randomized trial. PLACE AND DURATION OF STUDY Dermatology OPD, PNS Shifa Hospital, Karachi, from January to June 2013. METHODOLOGY Patients aged 18 - 50 years with localized alopecia areata were included in the study. Exclusion criteria ...

OBJECTIVES To continue assessment of the benefits and risks of intralesional administration of cidofovir, an acyclic nucleoside phosphonate, for treating severe recurrent respiratory papillomatosis (RRP) in pediatric patients, and to discuss guidelines for larger prospective multi-institutional studies of the use of cidofovir. DESIGN Prospective case series. SETTING Tertiary care children's...

INTRODUCTION Few studies have evaluated the efficacy of intralesional bleomycin injection combined with electroporation for the treatment of cutaneous tumors. However, the phenomenon that electroporation can enhance the cytotoxicity of bleomycin in vivo by 300-700 fold has been intensely investigated. CASE PRESENTATION Keratoacanthoma in an 86-year-old patient was treated with intralesional b...

Background: Common resistant-to-therapy warts pose a challenge to both clinicians and patients. Among many destructive and immunotherapeutic options, no single, fully effective treatment has been suggested yet. Many investigations, including those using intralesional antigen administrations, have demonstrated that cellular immunity plays a major role in the clearance of human papilloma virus (H...