We compare the efficacy of intratesticular ozone therapy with intraperitoneal ozone therapy in an experimental rat model. For this purpose, 24 rats were divided into four groups including sham-operated, torsion/detorsion, torsion/detorsion plus intraperitoneal ozone (O-IP), and torsion/detorsion plus intratesticular ozone (O-IT). The O-IP ozone group received a 4 mg kg-1 intraperitoneal injecti...

In the present study, we assessed the efficiency of four BMSC transplantation methods as a therapy for liver failure. A rat model (80 Sprague-Dawley rats) of D-galactosamine (D-gal)/lipopolysaccharide (LPS)-induced acute liver failure (ALF) was established and the rats were divided into 5 groups: a hepatic artery injection group, a portal vein injection group, a vena caudalis injection group, a...

the effect of cortisone on the experimental gastric ulceration produced by intraperitoneal injection of aspirin in the rat is studied. cortisone has significantly prevented the appearance of aspirin_ induced gastric ulceration. the possible mechanism of this effect of cortisone is discussed.

objective: crocin, as an active constituent of saffron, has many biological functions including antioxidant and anti-inflammatory activities. the present study was aimed to investigate the effects of crocin and chlorpheniramine on local edema induced by histamine. materials and methods: local edema was induced by subcutaneous injection of histamine (100 μl, 0.1%) in ventral surface of right hin...

The toxic effects of intraperitoneal, intrauterine and intravenous administration of quinacrine hydrochloride solution were evaluated in female adult rhesus monkeys (macaca mulatta). A single intraperitoneal injection of 400 mg and above resulted in the development of toxic manifestations leading to death of monkeys. In trauterine instillation of 500 mg of quinacrine was well tolerated and did ...

The intraperitoneal administration of PtCl4 or Pd(NO3)2 at levels of 28 or 56 mumole/kg body weight decreased the thymidine incorporation into DNA of spleen, liver, kidney, and testis. Spleen was most sensitive to both the platinum and the palladium salt. In liver, DNA syntheses in parenchymal cells and stromal cells were about equally sensitive to PtCl4. In control rats, only 20-30% of the 3H ...

peritoneal adhesions are challenging in abdominal surgery. in spite of different kinds of treatments still no definitive and effective treatment is suggested. to determine the prevention effects of intraperitoneal (ip) methylene blue in post surgical adhesion formation 44 rabbits were randomly divided in two groups of equal number. group i received an intra peritoneal injection of a 1% suspensi...

Introduction and Objective: liver is an important body organ without which life is impossible. Cyclophosphamide is an alkylating agent widely used as an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. The present study aimed to find a suitable antioxidant and examine the effect of vitamin E and selenium on reducing the side effects of cyclophosphamide on liver as a vit...

The effects of injectable Tunceli garlic oil (Allium tuncelianum) on serum response rainbow trout were examined. Influence intraperitoneal (i.p.) injection administration (TGO) was evaluated some immunological factors trout. Fish weight 40 g i.p. injected TGO at doses 1% and 10%. Serum lysozyme activity, bactericidal myeloperoxidase, protein immunoglobulin levels measured days 3, 7, 14 21 after...