نتایج جستجو برای: intravenous administration

تعداد نتایج: 295121  

Journal: :Journal of the American Medical Association 1912

Background   Lipoprotein lipase activity can be increased by clofibrate. Clofibrate is used to reduce serum triglyceride level in adults. The aim of this study was to determine the effect of clofibrate on serum triglyceride and cholesterol level after administration of intravenous lipid in very low birth weight neonates. Method In a randomized double blind placebo – controlled study, 60 very lo...

2017
Gábor Gellért

Pharmacokinetics of intravenous and oral pulsed high-dose dexamethasone were studied in four patients with pemphigus vulgaris. Doses for dexamethasone were varied from 100 to 300 mg. Serum concentrations were measured by high-performance liquid chromatographic procedure with diode assay detection. Bioavailability was assessed by comparing the areas under the serum concentration-time curves foll...

Journal: :Biological & pharmaceutical bulletin 2002
Shigeru Kawakami Nao Ohshima Ryu Hirayama Masami Hi Al Takashi Kitahara Toshiyuki Sakaeda Takahiro Mukai Koyo Nishida Junzo Nakamura Mikiro Nakashima Hitoshi Sasaki

The purpose of this study was to modify the biodistribution and pharmacokinetics of tilisolol, a beta-blocker, using the palmitoyl prodrug approach. After intravenous administration of tilisolol and O-palmitoyl tilisolol in rats, drug concentrations were determined in blood, bile, urine, and several tissues. The concentration-time profiles of tilisolol and O-palmitoyl tilisolol were analyzed ph...

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