conclusions according to our results, the infusion of one liter normal saline will cause a statistically significant decrease only in bd, after one hour, in patients with moderate to severe iss. the changes in sbp, pr, cvp and also ph, hco3 and hb were not statistically remarkable. background the management of trauma patients is often difficult. the american college of surgeons suggests using a...

Dogs and cats frequently present to veterinarians in hypovolemic shock following trauma. Blunt trauma from motor vehicles is by far the most common cause of trauma, and intravenous fluid therapy is one of the most important modalities of shock management in these patients. This lecture will cover fluid therapy options and their indications in patients presenting with a variety of complications ...

BACKGROUND Enhanced recovery may be viewed as a comprehensive approach to improving meaningful outcomes in patients undergoing major surgery. Evidence to support enhanced recovery pathways (ERPs) is strong in patients undergoing colorectal surgery. There is some controversy about the adoption of specific elements in enhanced recovery "bundles" because the relative importance of different compon...

BACKGROUND Sufficient intravascular volume should be established for optimal graft function after renal transplantation. However, there is no recommendation for the type of fluid therapy post-operatively. We compared half-saline vs. normal saline and 1/3-2/3 intravenous fluid replacement after renal transplantation. METHODS We enrolled all patients who underwent kidney transplantation between...

AIM This study assesses the improvement in outcome for newborn infants by decreasing major complications associated with intravenous fluid therapy by using an in-line filter, and evaluates the economical impact this might have in relation to daily changing of i.v. lines. METHODS In a prospective controlled study, 88 infants were randomly assigned to receive either filtered (except for lipids,...

INTRODUCTION Hospitals have seen a rise in Medical Emergency Team (MET) reviews. We hypothesised that the commonest MET calls result in similar treatments. Our aim was to design a pre-emptive management algorithm that allowed direct institution of treatment to patients without having to wait for attendance of the MET team and to model its potential impact on MET call incidence and patient outco...

BACKGROUND Inappropriate prescribing of intravenous (IV) fluid, particularly 0.9% sodium chloride, causes post-operative complications. Fluid prescription is often left to junior medical staff and is frequently poorly managed. One reason for poor intravenous fluid prescribing practices could be inadequate coverage of this topic in the textbooks that are used. METHODS We formulated a comprehen...

Intravenous enzyme replacement therapy with iduronate-2-sulfatase is an approved treatment for Hunter syndrome, however, conventional intravenous delivery cannot treat the neurologic manifestations of the disease due to its limited central nervous system penetration. Intrathecal administration of iduronate-2-sulfatase for delivery to the central nervous system is currently under investigation. ...

Background: Post-operative nausea and vomiting (PONV) following surgical operations requiring general anesthesia are common and distressing. The incidence of PONV may be as high as 70% during the first 24 hrs of tonsillectomy. Objective: This study determines the effects of intraoperative well-hydration on postoperative nausea and vomiting. Methods: 90 ASA I patients with age of 6-12 years sche...

BACKGROUND The purpose of this retrospective study was to present our assessment of modifiable perioperative factors for major cardiac and cerebrovascular events (MACCE). METHODS This study included an unselected cohort of patients with head and neck cancer (n = 456) treated in Turku University Hospital between 1999 and 2008. RESULTS Perioperative and postoperative univariate predictors of ...