Background: Dairy products were recognised in the late 1950s as food group exhibiting most anticaries activities. Yogurt, a dairy product, almost as commonly consumed as milk has been subjected to less research in the context of its effect on oral health, especially on dental enamel. AIM: To compare invitro the effectiveness of probiotic enriched yogurt extract and traditional yogurt extract in...

Type 2 diabetes mellitus is characterised via way of means insulin resistance and innovative β mobileular Failure; therefore, secretagogues are beneficial for attaining enough glycemic control. Glimepiride a second-era sulfonylurea that stimulates pancreatic cells to launch Insulin. Additionally, has been proven paintings thru numerous more mechanisms. It Is administered as monotherapy in suffe...

Despite of its effective anti-tumour activity,L-Asparaginase has limited clinical application due to the high rate of clinical hypersensitivity. In an attempt to develop a liposomal drug delivery for L-Asparaginase, enzyme loaded liposomes were formulated using soy lecithin, cholesterol and charge inducers by thin film hydration method. The effect of various components of the liposomes includin...

Paracetamol (PCM) is a non-steroidal anti-inflammatory drug (NSAID), sparingly soluble and bitter in taste. It is widely used as an analgesic and antipyretic. Solid dispersion of drug with different polymers was attempted to improve solubility of paracetamol.The aim of this study was to prepare, characterize and compare solid dispersions of poorly water soluble non-steroidal anti-inflammatory d...

Primordial germ cells (PGCs) are the precursors of the germ cell lineage. A method for the prolonged invitro culture of chicken PGCs, which retain the ability to colonise the gonad when introduced into developing embryos, has been described (van de Lavoir etal., Nature 441 (2006) 766–769). The invitro culture of PGCs provides a useful tool for the creation of transgenic chickens and investigati...

Metformin hydrochloride is biguanide used as oral hypoglycemic agent. But its shows short biological half life (t1/2 3-4) which leads to high dosage frequency. Therefore, the present study aims to prepare the controlled release formulation of metformin hydrochloride loaded in the chitosan microspheres. It also involves the study of the effect drug to polymer ratio on the performance of chitosan...