It is difficult to get a balanced picture of any new form of treatment, and much more difficult when new modes of diagnosis and therapy extend into the realms of atomic physics. In this article an attempt will be made to describe the present position of radioactive isotopes as applied' to surgery. Without going deeply into the physics of the subject, the author will present the principles under...

BACKGROUND The great clinical potential of myocardial β-AR imaging has been shown by recent studies evaluating the β-AR-specific, non-selective agent [(11)C]-CGP12177 in the setting of idiopathic-dilated cardiomyopathy, and myocardial infarction. However, the short half-life of (11)C hampers the potential of [(11)C]-CGP12177 for routine clinical use. AMI9 is an analog of the β-adrenoceptor liga...

Large quantities of radionuclides have leaked from the Fukushima Daiichi Nuclear Power Plant into the surrounding environment. Effective prevention of health hazards resulting from radiation exposure will require the development of efficient and economical methods for decontaminating radioactive wastewater and aquatic ecosystems. Here we describe the accumulation of water-soluble radionuclides ...

Introduction The conversion of tyrosyl residues into iodo-derivatives can be brought about under different ex­ perimental conditions [1 -3 ] and is essentially an electrophilic substitution by iodine at the phenolic ring of tyrosine. This reaction has been performed for different purposes in protein chemistry, e.g. the iodination of tyrosine has been extensively used in the preparation of label...

Immunoglobulin G (IgG) antibodies to carcinoembryonic antigen (CEA) were labelled with radioactive indium (111In) or iodine (131I) and a comparison made of their value in locating CEA producing tumours. Eleven patients given 111In-anti-CEA had 31 tumours as judged by a combination of all techniques. Of these, 28 were detected by 111In-anti-CEA and 26 by conventional clinical techniques. Five of...

The most dramatic effect of exposure to fallout from the Chernobyl accident on physical health has been the increase in thyroid cancer. When this was first reported 1,2, there was scepticism in Europe and the US, as it was not thought plausible that exposure to radio-isotopes of iodine in fallout could lead to such an increase in thyroid cancer with such a short latency. This review will discus...

Analyses of xenon from well gas rich in carbon dioxide reveal a large excess of radiogenic xenon-129 from the decay of extinct iodine-129. Smaller excesses observed in the heavy xenon isotopes are from fission. These results place narrow limits on any age difference between the earth and the oldest meteorites. The occurrence of excess radiogenic xenon-129 in well gas also suggests that any quan...

The Ordovician (Hirnantian; 445 Ma) hosts the second most severe mass extinction in Earth history, coinciding with Gondwanan glaciation and increased geochemical evidence for marine anoxia. It remains unclear whether cooling, expanded oxygen deficiency, or a combination drove Late Mass Extinction (LOME). Here, we present combined iodine sulfur isotope data from three globally distributed carbon...

iodine deficiency is the most important preventable cause of mental deficiency. the aim of this study was to specify the phase during fetal and postnatal development when iodine supplementation would have optimum effect on the prevention of brain damage. materials and methods forty schoolchildren aged 7-13 years, from the previously iodine deficient villages of kiga and randan, were divided int...

BACKGROUND The origin of the reduction in thyroid uptake after a low activity iodine scan, so-called stunning effect, is still controversial. Two explanations prevail: an individual cell stunning that reduces its capability to store iodine without altering its viability, and/or a significant cell-killing fraction that reduces the number of cells in the tissue still taking up iodine. Our aim is ...