The analysis of polymeric materials can be quite challenging because such samples are often of complex nature due to the presence of various groups of additives, compounding ingredients, and fillers. Of special importance are stabilizers that protect the material from degradation by thermal stress during manufacture or from environmental impact during use. Apart from intact stabilizers, the deg...

Abbreviations: sFlt-1: Soluble fms-Like Tyrosine Kinase-1; PlGF: Placental Growth Factor; 2DE: 2-Dimensional Gel Electrophoresis; MALDI: Matrix-Assisted Laser Desorption/Ionization; TOF: Timeof-Flight; LC: Liquid Chromatography; ESI: Electrospray Ionization; C8: Complement Component 8; C9: Complement Component; MAC: Membrane Attack Complex; C3: Complement Component 3; C5a: Complement Component ...

the chemical components in the decoctions of chinese herbal medicines are not always the same as those in the crude herbs because of the insolubility or instability of some compounds. in this work, a high-performance liquid chromatography (hplc) coupled with electrospray ionization (esi) tandem mass spectrometry method was developed to explore dynamic variation patterns of aconitum alkaloids in...

A surface acoustic wave-based sample delivery and ionization method that requires minimal to no sample pretreatment and that can operate under ambient conditions is described. This miniaturized technology enables real-time, rapid, and high-throughput analysis of trace compounds in complex mixtures, especially high ionic strength and viscous samples that can be challenging for conventional ioniz...

The application of continuous flow-extractive desorption electrospray ionization (CF-EDESI), an ambient ionization source demonstrated previously for use with intact protein analysis, is expanded here for the coupling of reversed phase protein separations to mass spectrometry. This configuration allows the introduction of charging additives to enhance detection without affecting the chromatogra...

Positively charged helium droplets were produced by ionization of liquid helium in an electrostatic spraying experiment, in which fluid emerging from a thin glass capillary was ionized by applying a high voltage to a needle inside the capillary. At 2.2 K, fine droplets (<10 μm in diameter) were produced in pulsed sprays or showers with total currents as high as 0.4 μA at relatively low voltages...

the anthocyanins of the fruit skin of iranian forest pear (sange khouj) were separated, identified and quantified using high-performance liquid chromatography/diode array detection (hplc/dad) and hplc/electrospray ionization /mass spectrometry (hplc/esi /ms). the individual anthocyanins were identified by comparing their mass spectral data and retention times with those of standards and publish...

The lack of authentic standards has limited the quantitative analysis of herbal drugs in biological samples. The present work demonstrated a practicable strategy for the assay of herbs and their metabolites independent of authentic standards. A liquid chromatography–electrospray ionization–mass spectrometry (LC–ESI–MS) method for the qualitative and quantitative determination of the metabolites...

The coupling of liquid chromatography and mass spectrometry (LC/MS) has been established as one of the most powerful tools in analytical chemistry and has resulted in important advances especially in biomedical and biochemical research. The predominantly used interfaces are electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI). Non-polar compounds, however, are diffi...

The occurrence of emerging Fusarium mycotoxins beauvericin (BEA), enniatins (ENNs) (A, A1, B, B1), Fusaproliferin and moniliformin was evaluated by a liquid chromatography/electrospray ionization-tandem mass spectrometric (LC/ESI-MS/MS) technique in 65 domestic rice samples produced in Gilan and Mazandaran Provinces in IR Iran. The results showed that 46% of the samples were contaminated with a...