Polyglutamine (polyQ) sequences are found in a variety of proteins, and mutational expansion of the polyQ tract is associated with many neurodegenerative diseases. We study the amyloid fibril structure and aggregation kinetics of K2Q24K2W, a model polyQ sequence. Two structures have been proposed for amyloid fibrils formed by polyQ peptides. By forming fibrils composed of both (12)C and (13)C m...

Due to the increasing complexity of the design interactions between the chip and package, it is necessary to consider them at the same time. In order to simultaneously handle chip and package performances, co-design of chip and package is a widely adopted solution, particularly because the finger/pad locations significantly affect IR-drop of the core and the package routing. In this paper, we d...

High resolution laser induced fluorescence spectrum of IrB in the spectral region between 545 and 610 nm has been recorded and analyzed. Reacting laser-ablated iridium atoms with 1% B(2)H(6) seeded in argon produced the IrB molecule. This is the first experimental observation of the IrB molecule. Four vibronic transition bands, (v,0) with v=0-3 of an electronic transition system, have been obse...

MobiHealth is a European project (IST-2001-36006) that explores the possibilities of 2.5G and 3G networks to supportnew m-health services. Standard TCP/IP based Internet networking protocols are used to transport the m-health servicedata over these next generation broadband wireless networks.The MobiHealth m-health service is based on a telematics system that consists of three m...

The molecular structures of sulphonamides are interesting for evaluating their mobility in soils and preparing composite complexes optimizing the use these drugs. In this work, several arylsulfonamides along with conformational analysis tautomerism were investigated theoretically. spectroscopical properties arylsulfonamides, also studied at level by using a computational modeling quantum mechan...

Assignment model is a powerful operations research techniques that can be used to solve assignment or allocation problem. This study applies the assignment model to the course allocation problem in Nigeria tertiary institution in order to maximize lecturers’ effectiveness. A well-structured questionnaire was used to obtain data from lecturers and solved with Hungarian method. The study revealed...

One of the basic combinatorial optimization problems is the assignment problem that deals with assigning jobs to individuals. In traditional assignment problems, n jobs usually assign to n individuals such that the total cost is minimized or the total profit is maximized. However, in numerous real-life applications, various attributes could be considered in assignment problems while data (obj...

Modulated tone-burst light was employed to measure non-radiative relaxation time of fluorophores with biomedical importance through photoacoustic effect. Non-radiative relaxation time was estimated through the frequency dependence of photoacoustic signal amplitude. Experiments were performed on solutions of new indocyanine green (IR-820), which is a near infrared dye and has biomedical applicat...