Background: Platelets can activate B cells and stimulate them for the production of antibodies. Since platelet microparticles (PMPs) originate from platelets, they may have the same virtue. In the present study, the effect of PMPs was investigated on the production of human leukocyte antigen (HLA)-specific antibody from B cells in vitro. Materials and Methods: In this experimental study, HLA-D...

background: blood donation safety is one of the basic goals of the organization of blood transfusion in the world. self-exclusion and failed options are additional screening tests to routine diagnostic tests which is performed to detect the transmitted infection through blood or blood products. the purpose of this study was to investigate the efficacy of these systems on the improvement of bloo...

Background & Objective: Although the antigen expression patterns of acute lymphoblastic leukemia (ALL) are well known, this study attempted to evaluate commonly used immune markers for immunophenotyping of acute leukemia to set the minimum of necessary diagnostic panels by flow cytometry. Methods: This study evaluated 89 patients referred from all over th...

INTRODUCTION The prevalence of somatic chromosomal abnormalities in infertile male individuals has been reported to vary in different literatures. The aim of this study was to investigate the frequency of chromosomal aberrations among infertile men referred to the Cytogenetic Laboratory of Iran Blood Transfusion Organization Research Centre (IBTO). MATERIALS AND METHODS Chromosomal analysis w...

Seyed-Moayed Alavian MD 1, Masoud Ahmadzad Asl MD 2, Maryam Keshvari MD 3, Bita Behnava MD 4, Bashir Hajibeigi MD 5 1 Associate Professor of Gastroenterology; Department of Gastroenterology, Baqiyatallah University of Medical Sciences; Dean of Tehran Hepatitis Center, Tehran, Iran 2 Methodology and Statistics Consultant; Nikan Health Researchers Institute, Tehran Hepatitis Center, Tehran, Iran ...

introduction transfusion of red blood cells is a key component in the resuscitation of massively hemorrhaging patients post-injury. little is known about the functional status of patients at discharge or the outcome of patients after discharge from acute hospitalization. we assessed the changes among major trauma patients who had received massive transfusions. materials and methods this article...

Background: Blood donation safety is one of the basic goals of the organization of blood transfusion in the world. Self-exclusion and failed options are additional screening tests to routine diagnostic tests which is performed to detect the transmitted infection through blood or blood products. The purpose of this study was to investigate the efficacy of these systems on the improvement of bloo...

objective: to classify different types of acute leukemia based on cooperative game theory and shapley value. materials and methods: in this study, patients data were collected from flow cytometry tests of the iran blood transfusion organization (ibto) have been used. 304 different diagnosed samples in 8 classes of acute leukemia were investigated. samples were initially in numerical format. i...