نتایج جستجو برای: iron chelation

تعداد نتایج: 145419  

2013
Jessica L. Heath Joshua M. Weiss Catherine P. Lavau Daniel S. Wechsler

Iron is essential for normal cellular function. It participates in a wide variety of cellular processes, including cellular respiration, DNA synthesis, and macromolecule biosynthesis. Iron is required for cell growth and proliferation, and changes in intracellular iron availability can have significant effects on cell cycle regulation, cellular metabolism, and cell division. Perhaps not surpris...

Journal: :Thalassemia Reports 2012

Journal: :International journal of cardiology 2012
Razieh Sabet Mohaddeseh Behjati Rouhollah Vahabpour Arash Memarnejadian Mahboubeh Rostami Afshin Fassihi Mohammad R Aghasadeghi Lotfollah Saghaie Ramin Miri

2005
CHAIM HERSHKO GABRIELA LINK ABRAHAM M. KONIJN IOAV CABANTCHIK

Iron is one of the most common elements in nature. As a transition metal it is very efficient in electron transport and redox reactions. The proteins and enzymes in which iron is an essential component play a key role in respiration, energy production, detoxification of harmful oxygen species and cell replication. Despite the abundance of iron in nature, the solubility of its stable ferric form...

Journal: :Blood 2012
Janet L Kwiatkowski Hae-Young Kim Alexis A Thompson Charles T Quinn Brigitta U Mueller Isaac Odame Patricia J Giardina Elliott P Vichinsky Jeanne M Boudreaux Alan R Cohen John B Porter Thomas Coates Nancy F Olivieri Ellis J Neufeld

Morbidity and mortality in thalassemia are associated with iron burden. Recent advances in organ-specific iron imaging and the availability of oral deferasirox are expected to improve clinical care, but the extent of use of these resources and current chelation practices have not been well described. In the present study, we studied chelation use and the change in iron measurements in 327 subje...

Journal: :Journal of Toxicology: Clinical Toxicology 1982

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