نتایج جستجو برای: isogenic line
تعداد نتایج: 416281 فیلتر نتایج به سال:
MTAP deletions occur in 10–15% of all human cancers, providing one the largest precision oncology patient populations. MTA-cooperative PRMT5 inhibitors leverage well-characterized synthetic lethal relationship between inhibition and MTAP-deletion. TNG908, AMG 193, MRTX1719 are clinical stage for treatment MTAP-deleted solid tumors. TNG462 is an investigational inhibitor with significantly enhan...
Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease primarily affecting the cerebellum. Very little is known about the molecular mechanisms underlying the disease and, to date, no cure or treatment is available. We have successfully generated bona fide induced pluripotent stem cell (iPSC) lines of SCA2 patients in order to study a disease-specific phenotype. Here, we demonstrate...
abstract according to increase in electricity consumption in one hand and power systemsreliability importance in another , fault location detection techniqueshave beenrecentlytaken to consideration. an algorithm based on collected data from both transmission line endsproposed in this thesis. in order to reducecapacitance effects of transmission line, distributed parametersof transmission line...
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