A 13-year-old girl presented with multiple skin abscesses. She was diagnosed as having juvenile dermatomyositis (DM) at the age of 7 years. She had suffered from recurrent skin infections, atypical pruritic dermatitis and pneumonia since the age of 8 years. Bacteriologic and fungal cultures for skin abscesses and oral mucosa were positive S. aureus and C. albicans, respectively. Chemotactic def...

Systemic sclerosis (SS) and dermatomyositis (DM) are both multisystem disorders and share some common clinical features. We report here an 11 year-old girl whose disease showed a changing clinical pattern from juvenile systemic sclerosis (JSS) to slowly progressing juvenile dermatomyositis (JDM) and had associated generalized morphea. Serological studies revealed antinuclear antibodies (ANA) wi...

Background Juvenile Dermatomyositis (JDM) is a systemic autoimmune inflammatory muscle disorder and vasculopathy that affects children younger than 16 years old. JDM was not associated with development of malignancies, unlike adult dermatomyositis. Nasopharynx carcinomas (NPC) are rare tumors, corresponding to 2% of tumors of the head and neck and 0,25% of all tumors. They are closely related t...

Of the diseases within the spectrum of the juvenile idiopathic inflammatory myopathies, juvenile dermatomyositis (JDM) is the most common. As the name implies, JDM affects the muscles and skin most commonly, but can involve other organ systems as well. Dermatologic manifestations often precede other signs and symptoms by months or even years and frequently are the primary reason the patient see...

Introduction Juvenile dermatomyositis (JDM) is a rare chronic, autoimmune vasculopathic disease with mainly muscle and skin involvement. The incidence described in USA is 2.5-4.1 cases per million children; the disease is slightly more common in girls. Recent studies describe that two third of the patients followed a chronic disease course, whereas only one third showed monocyclic disease course.

Materials and methods 16 patients (9 girls) with diagnosis of JDM (age 3–16,2 yrs) performed pulmonary function tests (PFT). 14 were receiving treatment; all had muscular testing. 13 had weakness as major symptom. Respiratory symptoms: dry cough in 2/16; reduced exercise tolerance: 3/16. Chest xray: normal in 13/13. Echocardiogram and ECG: normal in all. 9/16 had positive ANA-Ab; antiJO1 Ab neg...

A series of 29 children with dermatomyositis has been reviewed and the outcome compared between cases treated by us initially with a low dosage short duration course of corticosteroids, and those referred late and having had various different therapeutic regimens and usually more active and higher dosage drug schedules. There were fewer relapses and less morbidity in the low dosage short term g...

38 Volume 25 Number 1 over the bridge of the nose along with a purplish rash over her eyelids that had been present for approximately 6 to 8 weeks. In addition, the child had a pruritic bumpy rash on her upper arms, elbows, knuckles, and knees and an elongated purplish area on her right shin. The child’s mother stated, “The facial rash seems to worsen after she has been in the sun.” The mother ...

Juvenile dermatomyositis (JDM) is the most common form of juvenile idiopathic inflammatory myopathy. We report a child with steroid-dependent JDM refractory to hydroxychloroquine and subcutaneous methotrexate who experienced systemic reactions to intravenous immunoglobulin and was successfully treated with subcutaneous immunoglobulin. This form of therapy has been shown to be safe, has a very l...