نتایج جستجو برای: juvenile xanthogranuloma
تعداد نتایج: 45709 فیلتر نتایج به سال:
Juvenile xanthogranuloma (JXG) is a benign histiocytic disease of uncertain pathogenesis that usually appears as a cutaneous lesion(s) in the head and neck region of young children. Diagnosis is based on histological examination that shows a nodular, dense infiltrate of polygonal or spindled mononuclear cells with moderate amounts of cytoplasm and scattered Touton giant cells. Juvenile xanthogr...
Juvenile xanthogranuloma (JXG) is a rare histiocytic disorder that is usually benign and self-limiting. We present a case of atypical, aggressive JXG harboring a novel mitogen-activated protein kinase (MAPK) pathway mutation in the MAPK1 gene, which encodes mitogen-activated protein kinase 1 or extracellular signal-regulated 2 (ERK2). Our analysis revealed that the mutation results in constitut...
Intraocular lacrimal gland tissue is an extremely rare choristoma. A newborn girl was seen with a fleshy, vascular tumor arising from the peripheral iris and the anterior chamber angle. The tumor was treated with topical steroids on suspicion of a juvenile xanthogranuloma; later, it grew slightly and a secondary glaucoma developed. Histopathological examination of the resected tumor showed lacr...
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