The keratinolytic activities of dermatophytes which parasitize skin, nails, and hair have been described previously (1, 3, 6, 8); however, the isolation of a keratinase from these organisms has not yet been reported. Trichophyton mentagrophytes var. granulosum (T. granulosum Sabouraud, 1909) was grown in a keratin medium composed of (per liter): horse hair, 2.5 g; glucose, 0.9 g; MgSO4.7H20, 0....

The Actinomycetes comprise a ubiquitous order of bacteria which exhibits wide physiological and morphological diversity. These microorganisms are particularly abundant in alkaline soils rich in organic matter. Keratin is an insoluble structural protein of skin, and its derivatives (e.g. feather, hair, wool and horn) are known for their high stability. Actinomycetes producing keratinases are hav...

IT is well known that sclero-proteins are not readily digested by the enzymes of vertebrates; both pepsin and trypsin act upon elastin, collagen is very resistant to trypsin but is digested by pepsin, and keratin is not attacked by either enzyme. However, Stankovic, Arnovlzevic and Matavulj [1929] have described a keratinase from the crops of certain birds of prey and Ssadikov [1927] has claime...

Feather waste is generated in large amounts as a by-product of commercial poultry processing. This residue is almost pure keratin, which is not easily degradable by common proteolytic enzymes. Eight strains of Bacillus, isolated from decomposing feathers were tested for the hydrolysis of feather wastes in the laboratory. Among these strains, Bacillus cereus KB043 was the best feather degrading ...

A distinctive isolate was discovered and visually recognized as a member of the genus Didymella during routine examination Coelomycetes isolated from diverse fruit juices. Based on sequencing internal transcribed spacer (ITS), fungus identified keratinophila since it showed 100% identity to type strain. The strain thrived produced keratinase collagenase enzymes by hydrolyzing native chicken fea...

Keratinases are a group of proteolytic enzymes that display the capability of degrading insoluble keratin substrates such as feather resulting as poultry waste. Entrapment of crude/purified enzyme within a matrix is a common method for immobilization. An immobilized enzyme provides increased resistance to changes in conditions such as pH or temperature. It also allows enzymes to be held in plac...

background and objectives: dermatophytes possess a wide array of virulence factors and various antifungal susceptibility patterns which influence their pathogenesis in humans and animals. the aim of this study was to evaluate antifungal suscep- tibility and keratinase and proteinase activity of 49 dermatophyte strains from the genera microsporum , trichophyton and epidermophyton which were isol...

The keratinase from Stenotrophomonas maltophilia (KerSMD) is known for its high activity and pH stability in keratin degradation. However, catalytic efficiency and detergent tolerability need to be improved in order to be used for industrial application. In this work, we obtained several keratinase variants with enhanced catalytic efficiency, thermophilicity, and anti-salt and detergent tolerab...