BACKGROUND Odontogenic keratocyst (OKC) is a developmental odontogenic cyst with an aggressive clinical behavior suggesting a change in its terminology from a cyst to a tumor and has now been renamed as keratocystic odontogenic tumor (KCOT). The purpose of this study was to assess and compare angiogenesis in ameloblastoma and OKC. MATERIALS AND METHODS Angiogenesis was assessed by studying th...

PATHOGENESIS OF KERATOCYSTIC ODONTOGENIC TUMOR-A REVIEW Sunayana Tandon, 1 Khushboo Phull, 2 Piyush Tandon Reader, 1 Senior Lecturer, 2 Reader, 1. Department of Oral & Maxillofacial Surgery, Teerthanker Mahaveer Dental College & Research Center, Moradabad, Uttar Pradesh 2. Department of Oral Pathology & Microbiology, Teerthanker Mahaveer Dental College & Research Center, Moradabad, Uttar Prades...

Multiple keratocystic odontogenic tumors are one of the key features of Gorlin-Goltz syndrome. A 15-year-old nonsyndromic female child presented with multiple keratocystic odontogenic tumors. The presence of the tumors was observed in immunological examinations. The images led to the suspicion of Gorlin-Goltz syndrome which was discarded after analyzing the patient's medical history and complem...

Carnoy’s solution was first used as a medicament in surgery by Cutler and Zollinger in 1933. The reformulated carnoy’s solution without chloroform is accepted because exposure to chloroform has been associated with cancer and reproductive toxicity. It is assumed that carnoy’s solution eradicates epithelial rests from the cyst wall and reduces the rate of recurrence. In the world health organiza...

Glandular odontogenic cyst (GOC) is considered an odontogenic cyst of developmental origin, which because of its histological features had been termed sialo-odontogenic cyst. Although clinically and radiologically they bear similarity to relatively innocuous periapical lesions, their biological behavior is comparable to aggressive tumor-like conditions-like keratocystic odontogenic tumors. Thei...

The keratocystic odontogenic tumor, although a benign lesion, is peculiarly aggressive with a high recurrence rate. Its involvement with the maxillary antrum is atypical. We report the unusual case of a 20-year-old male patient with an extensive antral tumor associated with an impacted third molar, which was initially misdiagnosed as a dentigerous cyst. Clinical, radiographic, and histopatholog...

Midkine (MK; a low molecular weight heparin-binding growth factor) is a multifunctional cytokine. MK plays a role in morphogenesis of many organs including teeth through epithelial-mesenchymal interactions. We immunohistochemically examined MK expression in various human odontogenic tumors. There was no difference in positive rate and intensity of MK between benign odontogenic tumors and their ...