Systemic ketosis was induced in first-parity gilts by the isocaloric substitution of glucose with 1,3-butylene glycol to supply 20% of the total dietary energy beginning on d 23 (23 BG) or d 60 (60 BG) of gestation. Ketosis reduced (P less than .05) maternal plasma glucose, urea N and insulin concentrations. Fetal carcass dry matter and carcass glycogen contents were reduced (P less than .05) b...

Impaired mitochondrial function often results in excessive production of reactive oxygen species (ROS) and is involved in the etiology of many chronic diseases, including cardiovascular disease, diabetes, neurodegenerative disorders, and cancer. Moderate levels of mitochondrial ROS, however, can protect against chronic disease by inducing upregulation of mitochondrial capacity and endogenous an...

The current concept of fatty acid metabolism involves the formation of acetyl CoAl and the condensation of acetyl CoA with oxalacetate upon entrance into the tricarboxylic acid cycle. Therefore, a sufficient amount of oxalacetic acid is necessary for the complete oxidation of fatty acids via the tricarboxylic acid cycle, and, if sufficient oxalacetic acid is not present., ketosis results. Previ...

Metabolic disorders in animals are one of the most important problems in modern cattle production. The paper presents results characterising the functional state of the liver in dairy cows with clinical ketosis. The study was conducted on 17 Holstein cows (9 of them were clinically healthy with negative test for ketone bodies in urine and 8 with positive test) in their second to fourth lactatio...

BACKGROUND The mechanism of a high-fat, low-carbohydrate ketogenic diet (KD) in alleviating drug-resistant epilepsy is unknown but may be related to systemic ketosis induced under this treatment. The need for frequent measurement of systemic ketosis, which is essential for improving maintenance of the KD in patients and for studying mechanism of the KD action, has prompted us to validate the br...

Introduction Diabetes mellitus till recently has beeen divided into two main types-the 'juvenile' and 'maturity onset'-on the basis of the age at onset, bodyweight, susceptibility to ketosis and response to insulin and oral therapy. Lawrence (1951) described a rare variety of lipo-atrophic diabetes characterized by earlier age of onset, loss of subcutaneous fat, rarity of ketosis and high insul...

Research of the frequency increased ketone bodies in cows during transition period three weeks before calving and after should determine tendency Holstein breed to ketosis. It is also important investigate relationship between changes blood biochemical parameters development treatment The purpose study was effectiveness using a probiotic strain bacteria subclinical ketosis drying off calving. f...