Purpose: Chronic stress represents a critical influence on ageing of Leydig cells in testis. We aimed to investigate expression changes of microRNA (miRNA) associated with stress-induced ageing in Leydig cells. Methods: Brown Norway rats were separated into three groups, young control group, stress group and age group. Physiological changes, including serum corticosterone and testosterone level...

The management of cerebral glioma (CG) remains challenging. Recently, methods based on the study expression levels miRNAs in blood plasma have proven to be promising. volume tumor tissue is known correlate with increased microRNA-21 and -210. MicroRNA-15, -16, -34, -126 -342 are involved regulation proliferative potential, microRNA-128 metabolic activity. aim was evaluate extended protocol for ...

To investigate the role of circ_0084927 in lung cancer cell sensitivity to cisplatin. Half-maximal inhibitory concentration value cisplatin was detected by counting kit-8. and microRNA-634 expression were determined reverse transcription quantitative polymerase chain reaction. Cell kit-8, scratch healing, colony formation as well Transwell experiments used for analyzing viability, healing rate,...

Objectives: To analyse CPEB3 using bioinformatic tools in several types of cancer, various HNSCC cell lines based on cancer stages, tumour grades and the gene interaction, protein regulating pathway, microRNA survival analysis. Methods: Bioinformatics used were UALCAN, TCGA, NCBI, GEPIA, Oncomine, cBioPortal, Human Protein Atlas, STRING, Metascape, miRNA Target Prediction Database. Findings: ex...