Weight management a. We suggest the maintenance of a stable (within 5%), healthy weight as it is associated with a lower risk of developing chronic kidney disease (2C) b. We suggest, where weight loss is required, the use of medications such as topiramate (if available) in conjunction with a non-pharmacological weight loss programme to increase weight loss and reduce the risk of developing chro...

conclusions oral mg supplementation did not protect the cp induced nephrotoxicity in diabetic rats. results cp administration in normoglycemic rats significantly elevated the serum levels of blood urea nitrogen (bun) and creatinine (cr) (p < 0.05). however, coadministration of cp and mg statistically increased the serum levels of bun and cr in both normoglycemic and diabetic animals when compar...

In autosomal recessive polycystic kidney disease (ARPKD), progressive enlargement of fluid-filled cysts is due to aberrant proliferation of tubule epithelial cells and transepithelial fluid secretion leading to extensive nephron loss and interstitial fibrosis. Congenital hepatic fibrosis associated with biliary cysts/dilatations is the most common extrarenal manifestation in ARPKD and can lead ...

Introduction: Correct interpretation of kidney images requires the knowledge of its normal&nbsp;size. This study aimed to establish normal values for kidney length and parenchymal thickness&nbsp;and identify the potential related factors in a group of Iranian adults. Methods: Renal dimensions, including length and parenchymal thickness were measured&nbsp;by sonography in 103 individuals with n...

Three experiments were conducted with 9-d-old crossbred chicks to determine the effect of supplemental L-cysteine.HCl.H2O on tolerance to excess dietary Cd. Cd levels of 30 or 60 mg/kg added to a fully fortified corn-soybean meal diet depressed both body weight gain and gain:feed ratio and increased kidney Cd concentration. Supplemental cysteine (i.e., .59% L-cysteine.HCl.H2O) did not alleviate...

Background: This study examined the effect of grape seed proanthocyanidin extract (GSPE) on lipid peroxidation content and activity of tissue antioxidant enzymes, including catalase, superoxide dismutase and glutathione peroxidase in diabetic rats. Methods: Thirty male rats were divided into three groups of 10 rats each: control, diabetic and diabetic groups that received 500 mg/kg GSPE for 6 w...

The majority of CKD-related complications stem from cardiovascular pathologies such as hypertension. To help reduce cardiovascular complications, aerobic exercise is often prescribed. Emerging evidence suggests high intensity interval training (HIIT) may be more beneficial than traditional aerobic exercise. However, appraisals of varying forms of aerobic exercise, along with descriptions of mec...

Our aim was to analyze whether birth weight contributes to future hypertension through reduced kidney volume, and could albuminuria be a marker of this pathway. We included 103 patients with newly-diagnosed essential hypertension and 92 normotensive controls. Blood pressure(BP) was measured using mercury sphygmomanometer and ABP monitor. Kidney volume was determined by ultrasound. Data on birth...