Inverse problem for the identification of parameters large-scale systems nonlinear ordinary differential equations (ODEs) arising in biology is analyzed. In a recent paper \textit{Mathematical Biosciences, 305(2018), 133-145}, authors implemented numerical method suggested by one \textit{J. Optim. Theory Appl., 85, 3(1995), 509-526} moderate scale models biology. This combines Pontryagin optimi...

Thermodynamic studies of equilibrium chemical reactions linked with kinetic procedures are mostly impossible by traditional approaches. In this work, the new concept of generalized kinetic study of thermodynamic parameters is introduced for dynamic data. The examples of equilibria intertwined with kinetic chemical mechanisms include molecular charge transfer complex formation reactions, pH-depe...