BACKGROUND Early mobilisation after stroke is thought to contribute to the effects of stroke-unit care; however, the intervention is poorly defined and not underpinned by strong evidence. We aimed to compare the effectiveness of frequent, higher dose, very early mobilisation with usual care after stroke. METHODS We did this parallel-group, single-blind, randomised controlled trial at 56 acute...

INTRODUCTION Immobilisation in the intensive care unit (ICU) leads to muscle weakness and is associated with increased costs and long-term functional disability. Previous studies showed early mobilisation of medical ICU patients improves clinical outcomes. The Surgical ICU Optimal Mobilisation Score (SOMS) trial aims to test whether a budget-neutral intervention to facilitate goal-directed earl...

Glaucoma is a multifactorial spectrum of diseases in which progressive optic nerve damage leading to blindness occurs with raised intraocular pressure as the main risk factor. The outfl ow of fl uids through the trabecular meshwork decreases when the iris moves forward and comes into contact with it. This condition is called “angle closure” and can lead to glaucoma damage if intraocular pressur...

Background: Healthcare policy encourages the use of scientific evidence in delivery healthcare services. However, complexity practice restricts codified knowledge clinical guidelines despite continued effort from policymakers to ensure their practice. This study adopts a mobilisation perspective explore multiple levels through which is enacted generate variation Aim: To how professionalised gro...

This critical review introduces a template that links phosphorus (P) sources and mobilisation processes to the delivery of P to receiving waters where deleterious impact is of concern. It therefore serves as a key introductory paper in this special issue. The entire process is described in terms of a 'P transfer continuum' to emphasise the interdisciplinary and inter-scale nature of the problem...

BACKGROUND Despite efforts to eradicate it, open defecation remains widely practiced in India, especially in rural areas. Between 2013 and 2014, 50 villages in one district of Odisha, India, received a sanitation programme under the Nirmal Bharat Abhiyan (NBA - "Clean India Campaign"), the successor of India's Total Sanitation Campaign. This paper documents the strategies and processes of NBA c...

Lumbar spine accessory movements, used by therapists in the treatment of patients with low back pain, is thought to decrease paravertebral muscular activity; however there is little research to support this suggestion. This study investigated the effects of lumbar spine accessory movements on surface electromyography (sEMG) activity of erector spinae. A condition randomised, placebo controlled,...

In the face of growing demand for sustainable sources biomass, challenge mobilising non-industrial private forest landowners (NIPF) with varying management objectives, to actively manage their forests and increase supply wood is an area research policy focus. While innovation knowledge exchange increasingly viewed as a means promoting mobilisation, structural weaknesses in sector such deficienc...

Rehabilitation has been shown to influence brain recovery and to reduce the number of patients who are left handicapped following stroke; however, a question emerges in terms of the optimal time-point to initiate mobilisation. Very early mobilisation involves starting mobilisation including sitting up, getting out of bed, standing and walking, soon after stroke and continuing at frequent interv...

INTRODUCTION High-dose therapy with haematopoietic progenitor cell support has increasingly been utilised for patients with haematological malignancies. Peripheral blood is the stem cell source of choice, however, various mobilisation strategies are used by different centres. PATIENTS AND METHODS Over a 2-year period, 52 patients with non-Hodgkin's lymphoma (median age 47 years, range 16-64 y...