Neural cell adhesion molecule L1 is a cell surface glycoprotein required for the correct development of the nervous system. L1 exists as two isoforms encoded by mRNA species that either collectively incorporate or exclude exons 2 and 27. Neurons utilize only the full-length isoform, whereas Schwann cells, kidney cells, and blood lymphocytes only express the short form of L1. Still other cells, ...

How the properties of a first language (Mandarin, Korean) influence the comprehension of sentences in a second language (English) was investigated in a series of self-paced reading time studies. Native Mandarinand Korean-speaking learners of English were compared with native English speakers on how they resolved a temporary ambiguity about the relationship between a verb and the noun following ...

Medical countermeasures to prevent or treat smallpox are needed due to the potential use of poxviruses as biological weapons. Safety concerns with the currently available smallpox vaccine indicate a need for research on alternative poxvirus vaccine strategies. Molecular vaccines involving the use of proteins and/or genes and recombinant antibodies are among the strategies under current investig...

In this paper, we nd the relationships between module contractibility of aBanach algebra and its ideals. We also prove that module contractibility ofa Banach algebra is equivalent to module contractibility of its module uniti-zation. Finally, we show that when a maximal group homomorphic image ofan inverse semigroup S with the set of idempotents E is nite, the moduleprojective tensor product l1...

Background: Mesenchymal stem cells are non-hematopoietic stromal cells that are used in the treatment of many chronic and autoimmune diseases by modulating the immune system. Due to the limitations of using autologous mesenchymal stem cells, the use of allogeneic stem cells is a promising therapeutic approach in the treatment of immunological disorders. This study aimed to investigate the abili...

BACKGROUND Programmed death-1 (PD-1) receptor/PD-1 ligand (PD-L1) pathway negatively regulates T-cell-mediated responses. The prognostic impact of PD-L1 expression needs to be defined in urothelial carcinoma (UC). PATIENTS AND METHODS Formalin-fixed paraffin-embedded tumor samples from 160 patients with UC were retrieved. PD-L1 expression was evaluated by immunohistochemistry using a mouse mo...

This study investigated whether and how the role of pitch fall in the first language (L1) interacts with its use as a cue for Japanese phonological vowel length in the second language (L2). Native listeners of Japanese (NJ) and L2 learners of Japanese with L1 backgrounds in Mandarin Chinese (NC), Seoul Korean (NK), American English (NE), and French (NFr) participated in a perception experiment....

background: cervical cancer has been shown to be highly associated with human papillomavirus (hpv) infection. the viral oncogenes e6 and e7 are constantly expressed by the tumor cells and are therefore potent targets for therapeutic genetic vaccination. in the present study, it was investigated the potential effect of hpv-16 e6, e7 and l1 co-administration to activate specific cytotoxic t lymph...

abstract background ulcerative colitis (uc) is characterized by recurrent episodes of inflammation limited to the mucosal layer of the colon. calprotectin is a zinc and calcium binding protein derived from neutrophils and monocytes. it is easily detectable in tissue samples, body fluids, and stools, which makes it a potentially valuable marker of inflammation. the aim of the current study is to...