OBJECTIVES Neonates with congenital heart disease may appear hemodynamically stable after operation and then suddenly experience catastrophic decompensation. An improved means of predicting which infants will suddenly die in the early postoperative period may lead to lifesaving interventions. Studies indicate that blood lactate level is proportional to tissue oxygen debt, but information linkin...

Lactic acid (2-Hydroxypropanoic acid) or lactate (ionic form of lactic acid) is generated from pyruvic acid under anaerobic condition in all tissues like skeletal muscle, brain, RBC and kidney. The normal level of lactic acid in serum is in the range of 0.5-2.2 mM. During exercise and extensive work, its level in blood increases upto 12 mM and 25 mM. Lactate level is measured in dairy products ...

INTRODUCTION There has been an increase in patients having serum lactate drawn in emergency situations. The objective of this study was to determine whether or not it was necessary to obtain a lactate level in patients with a normal serum bicarbonate level and anion gap. METHODS This is a retrospective chart review evaluation of 304 patients who had serum lactate and electrolytes measured in ...

BACKGROUND During competition, high-performance swimmers are subject to repeated physical demands that affect their final performance. Measurement of lactate concentration in blood seeks to indirectly gauge physiologic responses to the increase in physical exercise. Swimmers face multiple maximal-exertion events during competition. Strenuous physical exercise leads to fatigue and, thus, a decre...

Background Lactate measurement is the key component in septic shock identification and resuscitation. However, point-of-care lactate testing is not widely used due to the lack of access to nearby test equipment. Biomarkers such as serum lactate, anion gap (AG), and base excess (BE) are used in determining shock in patients with seemingly normal vital signs. Purpose We aimed to determine if th...

The link between lactate generation and cellular acidosis has been questioned based on the possibility of H+ generation, independent of lactate production during glycolysis under physiological conditions. Here we test whether glycolytic H+ generation matches lactate production over a physiological pH and lactate range using ischemia applied to the hindlimb of a mouse. We measured the H+ generat...

Amaç: Çalışmamızda koroner arter bypass greft ameliyatı olan hastaların perfüzyon süresi ile kan laktat düzeyleri arasındaki ilişkinin karşılaştırılması amaçlanmıştır.Gereç ve Yöntem: Çalışmaya üçlü toplam 195 hasta dahil edildi. Hastalar kalp-akciğer makinesinden ayrıldıktan hemen sonra ölçülen düzeylerine göre iki gruba ayrıldı.Bulgular: Grupların ortalama arasında anlamlı fark vardı (p&l...