Edition 3(1) of the International Journal of Virtual and Personal Learning Environments (IJVPLE) contains four research articles and one book review. In the first paper, " Click If You Want to Speak: Reframing CA for Research into Multimodal Conversations in Online Learning , " Professor Marie-Noëlle Lamy from the UK Open University focuses on the neglected area of data collection visa -vis aud...

Hemoglobin Solutions Come of Age IN this issue of ANESTHESIOLOGY, Lamy et al. present their findings regarding the use of a commercially produced hemoglobin-based oxygen-carrying (HBOC) solution as an alternative to traditional allogeneic blood transfusions in patients who have undergone cardiac surgery. The study included a large number of patients (N 5 209) and involved the use of a commercia...

Cases of metaphysial dysplasia have been recorded by Pyle (1931), Bakwin and Krida (1937) and Hermel, Gershon-Cohen and Jones (1953). Jansen (1934) described a form of metaphysial dysplasia which he termed metaphysial dysostosis. Similar cases were reported by Cameron, Young and Sissons (1954), Lenk (1956), Maroteaux and Lamy (1960), Evans and Caffey (1958), and Gram, Fleming, Frame and Fine (1...

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau...

D. Lamy, C. Jeanthon, J. Ras, F. Van Wambeke, O. Dahan, M. T. Cottrell, D. L. Kirchman, and P. Lebaron UPMC Univ Paris 06, Observatoire Océanologique de Banyuls, 66650 Banyuls-sur-mer, France CNRS, UMR 7621, Laboratoire d’Océanographie Microbienne, LOMIC, Observatoire Océanologique de Banyuls, 66650 Banyuls-sur-mer, France UPMC Univ Paris 06, UMR 7144, Adaptation et Diversité en Milieu Marin, S...

Apparent deletion of the short arms of one X chromosome associated with clinically detectable abnormalities, has been reported (Jacobs, Harnden, Court Brown, Goldstein, Close, MacGregor, Maclean, and Strong, I960; Jacobs, Harnden, Buckton, Court Brown, King, McBride, MacGregor, and Maclean, I96I; de Grouchy, Lamy, Yaneva, Salomon, and Netter, I96I; London, Kemp, Ellis, and Mittwoch, I964). Howe...

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau...

Background Mucopolysaccharidosis VI (MPS VI, Maroteaux-Lamy syndrome) is an autosomal recessive lysosomal storage disorder determined by mutations in the arylsulfatase B gene located in chromosome 5. Pathogenic mutations of this gene result in reduced or absent activity of enzyme arylsulfatase B (N-acetylgalactosamine 4-sulfatase, ARSB). Incomplete degradation and cellular accumulation of glyco...