The responsibility of a Structural Engineer lies in not merely designing the structure based on safety and serviceability considerations but he also has to consider the functional requirements based on the use to which the structure is intended. While designing a power plant structure or a multi-storeyed building, the traditional structural steel framing consists of beams and girders with solid...

Cell invasion across basement membrane barriers is important in both normal development and cancer metastasis. In this issue of Developmental Cell, Naegeli et al. (2017) identify a mechanism for breaching basement membranes. Localized lysosome exocytosis fuels generation of large, invasive cellular protrusions that expand tiny basement membrane openings.

Methods The Amphia hospital is a large teaching hospital. In the third quarter of 2009 a BUN, defined by the national patient safety initiative, was introduced consisting of 4 components. 1) preoperative hair removal, 2) perioperative antibiotic prophylaxis, 3) normothermia and 4) limit the number of door openings. BUN compliance was measured every quarter by visual observations by dedicated in...

A simplified model of indoor short wave radiation couplings adapted to multi-zone simulations is proposed, thanks to a simplifying hypothesis and to the introduction of an indoor short wave exchange matrix. The specific properties of this matrix appear useful to quantify the thermal radiation exchanges between the zones separated by windows or large openings. Integrated in CODYRUN software, thi...

A mechanism connecting the local untwisting and opening of DNA double helix is proposed. The presented thermodynamical approach is based on two models: the Peyrard-Bishop model that describes the denaturation of DNA due to thermal fluctuations and the model developed by the author describing solitary torsional waves, which propagate along the DNA molecule forced by advancing RNA polymerase. The...

The Sicamous Creek Silvicultural Systems project examines clearcutting and silvicultural alternatives to clearcutting in high-elevation Engelmann spruce – subalpine fir (ESSF) forests, motivated by concerns about the effects of forestry practices on regeneration, hydrology, and biological diversity. Treatments include: ha clearcuts, arrays of -ha openings, arrays of .-ha patch cuts, indivi...

Nevus comedonicus is an uncommon variant of adnexal hamartoma and is considered a rare subtype of epidermal nevi. It was first described in 1895 by Kofmann who used the term “comedo-nevus”. It manifests as a group of closely dilated follicular openings with dark keratin plugs resembling comedones. Both unilateral and bilateral distributions are seen. The face is the most commonly affected site ...

Dilated pore was originally designated as a secondary or acquired trichoepithelioma by Winer, represents an appendageal tumor with differentiation towards hair structures. It is clinically characterized by having the appearance of a large blackhead filled with keratinous material. To the best of our knowledge, there has been no report of a dilated pore with four openings. We herein describe suc...