T he identification of clinically relevant end-points for use in clinical trials of new treatments in cystic fibrosis (CF) lung disease is an ongoing problem for physicians and researchers working in the field of CF care. Lung disease almost certainly starts in early infancy [1–6] and is progressive, leading to significant structural lung disease in the preschool years [7]. Despite this, the ma...

A spatiotemporally defined LCI is also needed to enhance the environmental impacts analysis and their optimization. Recent studies have shown that some environmental impact factors would require to be geodependently defined [3] and to be of use, the methodology requires a spatiotemporally defined LCI. Spatially defined LCI will also be useful to identify the sites of resources depletion and hig...

The study of intact, living cells using non-invasive optical spectroscopic methods offers the opportunity to assess cellular structure and organization in a way that is not possible with commonly used cell biology imaging techniques. We have developed a novel spectroscopic technique for diagnosing disease at the cellular level based on using low-coherence interferometry (LCI) to detect the angu...

Endoscopy has been widely used in diagnosing gastrointestinal mucosal lesions. However, there are still lack of objective endoscopic criteria. Linked color imaging (LCI) is newly developed endoscopic technique which enhances color contrast. Thus, we investigated the clinical application of LCI and further analyzed pixel brightness for RGB color model. All the lesions were observed by white ligh...

We analyze the signal to noise ratio (SNR) in a lensless compressive imaging (LCI) architecture. The architecture consists of a sensor of a single detecting element and an aperture assembly of an array of programmable elements. LCI can be used in conjunction with compressive sensing to capture images in a compressed form of compressive measurements. In this paper, we perform SNR analysis of the...

BACKGROUND Lung clearance index (LCI) derived from sulfur hexafluoride (SF6) multiple breath washout (MBW) is a sensitive measure of lung disease in people with cystic fibrosis (CF). However, it can be time-consuming, limiting its use clinically. AIM To compare the repeatability, sensitivity and test duration of LCI derived from washout to 1/30th (LCI1/30), 1/20th (LCI1/20) and 1/10th (LCI1/1...

Linked color imaging (LCI; Fujifilm Co., Tokyo, Japan) is a newly developed image-enhanced technique that has shown high diagnostic performance in the field of gastrointestinal endoscopy. LCI enhances color separation of the mucosal layer, making red regions redder and white regions whiter. This contributes to the detection of gastric cancer [1], ulcerative colitis [2], colorectal polyps [3, 4]...

The effects of a non-articulated SACH and a multiaxial foot-ankle mechanism on the performance of low-activity users are of great interest for practitioners in amputee rehabilitation. The aim of this study is to compare these two prosthetic feet and assess possible improvements introduced by the increased degrees of freedom provided by the multiaxial foot. For this purpose, a group of 20 hypomo...

This compendium provides extensions to the research first reported in the December 2005 Wood and Fiber Science Special Issue (WFS 2005) devoted to CORRIM’s Reports on Environmental Performance of Wood Building Materials. The Consortium for Research on Renewable Industrial Materials (CORRIM) is a nonprofit research consortium made up of 15 research institutions dedicated to developing comprehens...

Otitis media (OM) is the most common illness in children in the United States. Three-fourths of children under the age of three have OM at least once. Children with chronic OM, including OM with effusion and recurrent OM, will often have conductive hearing loss and communication difficulties, and need surgical treatment. Recent clinical studies provide evidence that almost all chronic OM cases ...