introduction:  the aim of this study was to compare the preventive effects of corticosteroids and curcumin on subglottic stenosis in an animal model.  materials and methods: twenty-one male german shepherd dogs were used for this study. after standardized trauma to the subglottic area, the dogs were divided into three groups. group a received curcumin (450 mg/ day) for 15 days; group b received...

The present paper explore out the better-characterized and most intensively studied oncogenic viruses of humans and animals. Many DNA and RNA viruses have been proved to be oncogenic (or carcinogenic) in a variety of animals, ranging from amphibia to primates, and évidence grows stronger that certain forms of human cancer are of viral origin. Several DNA viruses have been associated with the ca...

Suppressor of cytokine signaling 1 (SOCS1) is the key regulator of cytokine-mediated innate and adaptive immunity. One of the molecular mechanisms of SOCS1 is connected with inhibition of TLR4-NFkappaB pathway. The relationships among these molecules in laryngeal carcinoma are not exactly known. In this preliminary study we focused on their special activity and role in regulation of development...

A. Ferlito, MD, Department of Otolaryngology, University of Padua, Nuovo Policlinico, Via Giustiniani, 2, I-35100 Padua (Italy) Sarcomas originating in the larynx are extremely rare and form less than 1 % of all malignant laryngeal tumors. In the past, fibrosarcoma was considered as the most common malignant mesenchymal neoplasm in the larynx and it was generally held that at least half larynge...

"Sarcomatoid carcinoma is a rare and aggressive form of squamous cell (SCC). It biphasic tumor that has been shown to be dedifferentiated monoclonal classic carcinoma. The factors contribute proliferation SCC sarcomatoid are not precisely known but some studies revealed the importance anterior radiation therapy. This case report describes 62-year-old man, heavy smoker alcohol drinker diagnosed ...

Sarcomas account for less than 1% of malignant neoplasms arising in the head and neck in adults. Laryngeal synovial sarcoma is an extremely rare form of laryngeal malignancy with less than 20 cases reported in the literature. We report the case of a 48-year-old man with synovial sarcoma of the larynx. He underwent excision of the tumor followed by radiation. He is alive in remission at 36 month...

BACKGROUND The laryngeal schwannoma is a rare benign tumor of the larynx, most frequently found in the aryepiglottic fold, which can be rather bulky when diagnosed. METHODS We present a primary transoral robotic surgery (TORS) for a laryngeal schwannoma and highlight the advantages of the robotic assistance. RESULTS Thanks to the high-definition 3D dynamic vision and an improved freedom of ...

We describe a case of laryngeal amyloidoma in a 39-year-old man in whom CT examination disclosed a calcifield soft-tissue mass arising in the epiglottis. The presence of focal calcifications suggested a cartilaginous tumor.