Gene expression profiling has been used extensively in multiple fields of research to compare disease and control samples, to investigate mechanisms of disease, to identify subtypes within a heterogeneous clinical phenotype and to establish responses to a specific treatment. In addition, it can also be used to determine the function of a gene, to monitor changes over time, or for discovering ce...

In March-April 2016, 3288 original tweets tagged with #MND #ALS and other minor related tags (e.g., #cureALS #cureMND) were analysed using mixed quantitative and qualitative methods on tweet data and content. In this paper we outline the technical methods used in gathering and selecting relevant tweets for analysis, and present the results including inductive coding of content themes. The findi...

Recently, the use of the algorithmic lateral inhibition (ALI) method in motion detection has shown to be very effective. The promising results in terms of the goodness of the silhouettes detected and tracked along video sequences lead us to accept the challenge of searching for a real-time implementation of the algorithms. This paper introduces two steps towards that direction: (a) A simplifica...

Approximately 80% to 95% of patients with Amyotrophic Lateral Sclerosis (ALS) eventually develop speech impairments (Beukelman et al., 2011), such as defective articulation, slow laborious speech and hypernasality (Duffy, 2013). The relationship between impaired speech and asymptomatic speech may be seen as a divergence from a baseline. This relationship can be characterized in terms of measura...

The influence of light/dark adaptation and lateral inhibition on phototaxic foraging. Abstract Vision did not arise and evolve to just " see " things, but rather to act on and interact with the habitat. Thus it might be misleading to study vision without its natural coupling to vital action. Here we investigate this problem in a simulation study of the simplest kind of visually-guided foraging ...

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INTRODUCTION Textbook representations of the genicular arterial anastomosis show a large direct communication between the descending branch of the lateral circumflex femoral artery (DBLCFA) and a genicular branch of the popliteal artery but this is not compatible with clinical experience. The aim of this study was to determine whether the arterial anastomosis at the knee is sufficient, in the e...