The ventrolateral hypothalamus (VLH) in female guinea pigs includes a subset of neurons which contain estrogen and progestin receptors, and which are implicated in the regulation of female sexual behavior by steroid hormones. However, little is known about where these neurons project, and consequently which other brain areas are involved in sexual behavior in female guinea pigs. The anterograde...

GROSSMAN, S. P. AND J. W. HENNESSY. Differential effects of cuts through the posterior hypothalamus on ebod intake and body weight in male and female rats. PHYSIOL. BEHAV. 17(1) 89-102, 1976. Large knife cuts in the coronal plane through the posterior hypothalamus which transected the caudal connections of the medial hypothalamus without producing significant direct damage to cellular component...

The main focus of the self-stimulation phenomenon, as indicated by maximum rates for minimum stimulus levels and by lesion studies, iies in an olfactory midbrain pathway through septal area, lateral hypothalamus and ventrolateral tegmemum; over most of its course this pathway is called the medial forebrair bundle. The studies which indicated this "focus" also showed a gradient of self-stimulati...

Fibers projecting from several levels of the spinal cord to the diencephalon and telencephalon were labeled anterogradely with Phaseolus vulgaris leucoagglutinin injected iontophoretically. Labeled fibers in the thalamus confirmed projections previously observed. In addition, many labeled fibers were seen in the hypothalamus and in telencephalic areas not generally recognized previously as rece...

Although the hypothalamus is classified into more than 10 compartments, it still contains uncharacterized areas. In this study, we identified a new triangular-shaped area between the paraventricular hypothalamic nucleus (PVN) and the fornix area in the mouse anterior hypothalamus, which is enriched in chondroitin sulfate proteoglycans (CSPGs). We designated this region as the perifornical area ...

Aging is associated with a progressive decrease in appetite and food intake. Both A and B orexins, expressed in specific neurons of the lateral hypothalamic area, have been implicated in the regulation of sleep and feeding. In this study, the stimulatory effect of intracerebroventricular administration of the orexins on food intake was compared between young (4-mo-old) and old (25- to 27-mo-old...

The amygdala, prefrontal cortex, striatum and other connected forebrain areas are important for reward-associated learning and subsequent behaviors. How these structurally and functionally dissociable regions are recruited during initial learning, however, is unclear. Recently, we showed amygdalar nuclei were differentially recruited across different stages of cue-food associations in a Pavlovi...