A three-and-a-half year-old female Rahmani ewe was presented suffering from nervous symptoms. Grossly, a large cyst measuring 7 × 4 cm and weighing 145 g occupied the dilated left lateral ventricle. The overlying cerebral tissue was thin, atrophied and congested. It tore easily, and the cyst was evacuated spontaneously. Microscopically, liquefactive necrosis surrounded by aggregations of macrop...

—This paper presents a constrained self-organizing map (SOM) model for the visualization and reconstruction of the human brain lateral ventricle. The SOM model is a widely used method to approximate large and complex high dimensional data and reduce the data dimension for advanced applications. In our applications, the SOM model is used to deform a spherical network field to a 3D crooked brain ...

PURPOSE Neural stem and progenitor cells (NSPC) generate neurons and glia, a feature that makes them attractive for cell replacement therapies. However, efforts to transplant neural progenitors in animal models of brain injury typically result in high cell mortality and poor neuronal differentiation. METHODS In an attempt to improve the outcome for grafted NSPC after controlled cortical impac...

Disproportionate enlargement or isolation of the fourth ventricle are rare complications of ventriculo-peritoneal shunt for post-haemorrhagic hydrocephalus. Obvious features such as ataxia may indicate raised intracranial pressure in the posterior fossa. The child may, however, present with less specific signs of vomiting, anorexia, and lethargy and these symptoms may be misinterpreted as secon...

OBJECTIVES Lesions around interventricular foramen are difficult to remove for their important adjacent structures. We classify these tumors according their location on Magnetic Resonance Image (MRI) to help us resect these lesions. METHODS Thirty-two tumors around the interventricular foramen were studied according their location and anatomic relations in MRI. RESULTS Tumors around interve...

Previous studies demonstrated that thrombin is an important factor in brain injury after intracerebral hemorrhage. This study investigated the effect of thrombin on hydrocephalus development in a rat intraventricular hemorrhage (IVH) model. There were three parts in this study. First, male Sprague-Dawley rats had an injection of 200 μL saline, autologous blood or heparinized blood, into the rig...

Background and purpose Little is known about post-ischemic blood-cerebrospinal fluid (CSF) disruption. The source of CSF, choroid plexi, are selectively vulnerable to cerebral ischemia (1). This was previously addressed only in one experimental study by means of magnetic resonance imaging (MRI) (2). Evaluating past contrast-enhanced MRI studies executed in the acute phase of stroke, we noticed ...

Statistical shape analysis has emerged as an insightful method for evaluating brain structures in neuroimaging studies, however most shape frameworks are surface based and thus directly depend on the quality of surface alignment. In contrast, medial descriptions employ thickness information as alignment-independent shape metric. We propose a joint framework that computes local medial thickness ...