This is the final article in a four part series reviewing the influence of humor and laughter on physiological and psychological well-being. This final article reviews the evidence for the effect of sense of humor, exposure to a humor stimulus and laughter on various immune system components, with a focus on the effects of laughter on natural killer cell cytotoxicity.

The burst of laughter that is evoked by tickling is a primitive form of vocalization. It evolves during an early phase of postnatal life and appears to be independent of higher cortical circuits. Clinicopathological observations have led to suspicions that the hypothalamus is directly involved in the production of laughter. In this functional magnetic resonance imaging investigation, healthy pa...

A 69-year-old man had been suffering from recurrent syncope induced by laughter since the age of 58. His syncope was reproduced by head-up tilt testing with isoproterenol infusion and we concluded that his laughter-induced syncope was one type of neurally mediated syndrome (NMS). His daughter also had NMS and her syncope was treated with propranolol. Propranolol and midodrine hydrochloride, an ...

Laughter as a vocal expressive-communicative signal is one of the least understood and most frequently overlooked human behaviors. The chapter provides an overview of what we know about laughter in terms of respiration, vocalization, facial action, and body movement and attempts to illustrate the mechanisms of laughter and to define its elements. The importance of discriminating between spontan...

Hurling in Cornwall, la soule in Britanny, Shrovetide football in England: Popular games have normally been treated as forerunners of modern sport, sport having regulated the space and the time of the game, the (non-) violence of behaviour, the control of results, the planning, strategy, tactics, techniques and evaluation of the competitive action. This is told as a story of social improvement ...

Recent work has identified the physical features of smiles that accomplish three tasks fundamental to human social living: rewarding behavior, establishing and managing affiliative bonds, and negotiating social status. The current work extends the social functional account to laughter. Participants (N = 762) rated the degree to which reward, affiliation, or dominance (between-subjects) was conv...

Laughter is an important communicative signal in humanhuman communication. However, very few attempts have been made to model laughter animation synthesis for virtual characters. This paper reports our work to model hilarious laughter. We have developed a generator for face and body motions that takes as input the sequence of pseudophonemes of laughter and each pseudo-phoneme’s duration time. L...

Laughter is one of the most characteristic –and enigmatic– communicational traits of human individuals. Its analysis has to take into account a variety of emotional, social, cognitive, and communicational factors densely interconnected. In this article we study laughter just as an auditive signal (as a ‘neutral’ information carrier), and we compare its structure with the regular traits of lingu...

Automatic speech understanding in natural multiparty conversation settings stands to gain from parsing not only verbal but also non-verbal vocal communicative behaviors. In this work, we study the most frequently annotated non-verbal behavior, laughter, whose detection has clear implications for speech understanding tasks, and for the automatic recognition of affect in particular. To complement...

Although laughter can occur in various sequential (horizontal) patterns that have been well described, the voice quality components that can occur in laughter also need to be described in order to constitute a vertical array of possible phonetic contrasts. These components have been referred to as ‘states of the larynx’ and interact with pitch and with the ‘segmental’ components of laughter in ...