Cissus populnea has been used locally to treat many ailments such as venereal, stomach and skin infections; and also used as laxative or purgative. Economically it has been used as binder in food and in lining dye pits. This work aims at determining the type of anthraquinones from the stem bark of C. populnea which might be a potential source of drugs (laxative/cathartic) using thin layer chram...

Though others may have found this question hard to swallow (ba-dum-tcchh!), having the strength to be open about this is admirable. Finding yourself with a case of the runs can certainly put a damper on your whole sexual experience. While a semen allergy is one possible cause of dicey bowels, such allergies are quite rare. Perhaps you?ll be relieved to hear that it?s more likely that your diarr...

Though others may have found this question hard to swallow (ba-dum-tcchh!), having the strength to be open about this is admirable. Finding yourself with a case of the runs can certainly put a damper on your whole sexual experience. While a semen allergy is one possible cause of dicey bowels, such allergies are quite rare. Perhaps you?ll be relieved to hear that it?s more likely that your diarr...

BACKGROUND Mareya micrantha (Benth.) Müll. Arg. (Euphorbiaceae) is a shrub that is commonly used in Côte d'Ivoire (West Africa) for the treatment of constipation and as an ocytocic drug. The present study was carried out to investigate the laxative activity of Mareya micrantha in albino's Wistar rats. METHODS Rats were divided in 5 groups of 5 animals each, first group as control, second grou...

Definitive risk factors for constipation in palliative care remain poorly defined. A retrospective analysis of 211 admissions to a palliative care unit was undertaken, with the main aim being to identify some factors, which influence laxative prescription. On univariate analysis, significant unadjusted associations were found between two or more prescribed laxatives and a diagnosis of malignanc...

Opioid-related constipation is one of the most frequent side effects of chronic pain treatment. Enteral administration of naloxone blocks opioid action at the intestinal receptor level but has low systemic bioavailability due to marked hepatic first-pass metabolism. The aim of this study was to examine the effects of oral naloxone on opioid-associated constipation in an intraindividually contro...