The aim of this work was to evaluate, by an untargeted metabolomics approach, changes milk metabolites induced the replacement soybean hulls with cocoa husks in ewes’ diet. Animals were fed a diet integrated 50 or 100 g/d cacao husks. Milk samples analyzed ultra high performance liquid chromatograph coupled time flight mass spectrometer (UHPLC-QTOF-MS) platform. Multivariate statistical analysi...

The kiwifruit is cultivated globally due to its diversity of phytochemicals, especially phenolic compounds, which have antioxidant, anti-inflammatory and anti-cancer medical effects. However, only the pulp consumed, while peels cores—which are also rich in phytochemicals—are usually wasted. Meanwhile, detailed information on comparison among three parts still limited. In this study, antioxidant...

Saturn is orbited by a half dozen ice rich middle-sized moons (MSMs) of diverse geology and composition (e.g. Smith et al. , 1981; Thomas, 2010; Schenk et al. , 2011) that comprise ∼4.4% of Saturn’s satellite mass. The rest is Titan, more massive per planet than Jupiter’s satellites combined. Jupiter has no MSMs. Disk-based models to explain these differences exist (e.g. Sasaki et al. , 2010; C...

Liquid chromatography coupled to mass spectrometry (LC-MS) is an excellent technique to determine trace levels of polar and thermolabile pesticides and their degradation products in complex matrices. LC-MS can be equipped with several mass analyzers, each of which provides unique features capable to identify, quantify, and resolve ambiguities by selecting appropriate ionization and acquisition ...

Objective A highly sensitive and specifi c analytical method was developed for the qualitative and quantitative analysis of clonazepam (CLOZ) and its metabolite 7-aminoclonazepam (7-AC) in blood. The analytes were identifi ed by automated solid phase extraction-liquid chromatography-tandem quadrupole time-of-fl ight mass spectrometry (ASPELC-QTOF/MS) and quantitatively determined by automated s...

Comprehensive understanding of the roles and functions of lipids in cellular physiology and pathology requires unambiguous identification and accurate quantification of individual lipid molecular species. However, the enormous structural diversity of lipids (e.g., >37,000 lipid molecules cataloged in the LIPID MAPS database) presents a significant challenge in the high-throughput analysis of li...